Huang M, Feng S, Yang C, Wen F, He D, Jiang P
Chongqing Key Laboratory of Inorganic Functional Materials, College of Chemistry, Chongqing Normal University, Chongqing 401331, China.
Anal Methods. 2021 Mar 14;13(10):1247-1254. doi: 10.1039/d0ay02163f. Epub 2021 Feb 22.
MnO based electrochemical enzyme-free glucose sensors remain significantly limited by their low electronic conductivity and associated complex preparation. In this paper, an MnO nanosheet array supported on nickel foam (MnO NS/NF) was prepared using a simple hydrothermal synthesis and employed as a 3D integrated electrode for enzyme-free glucose detection. It was found that MnO NS/NF shows high performance with a wide linear range from 1 μM to 1.13 mM, a high sensitivity of 6.45 mA mM cm, and a low detection limit of 0.5 μM (S/N = 3). Besides, MnO NS/NF shows high selectivity against common interferences and good reliability for glucose detection in human serum. This work demonstrates the promising role of MnO NS/NF as an efficient integrated electrode in enzyme-free glucose detection with high performance.
基于MnO的电化学无酶葡萄糖传感器因其低电子导电性和相关的复杂制备过程而受到显著限制。本文采用简单的水热合成法制备了泡沫镍负载的MnO纳米片阵列（MnO NS/NF），并将其用作无酶葡萄糖检测的三维集成电极。研究发现，MnO NS/NF具有高性能，线性范围宽，从1 μM到1.13 mM，灵敏度高，为6.45 mA mM cm，检测限低，为0.5 μM（S/N = 3）。此外，MnO NS/NF对常见干扰物具有高选择性，对人血清中的葡萄糖检测具有良好的可靠性。这项工作证明了MnO NS/NF作为一种高效集成电极在高性能无酶葡萄糖检测中的广阔前景。
