Kraus V B, Baraniuk J N, Hill G B, Allen N B
Department of Medicine, Duke University Medical Center, Durham, NC 27701.
J Rheumatol. 1988 Feb;15(2):369-71.
We describe a hypogammaglobulinemic man with erosive oligoarticular septic arthritis due to Ureaplasma urealyticum. His clinical course was complicated by a subcutaneous abscess. Multiple synovial cultures were negative until finally cultures specific for mycoplasmas were performed. Serologic diagnosis cannot be relied upon in hypogammaglobulinemic patients because they do not mount a perceptible antibody response. This underscores the importance of a high clinical suspicion of mycoplasmas as etiologic agents of septic arthritis in this population and early communication with the microbiology laboratory so that appropriate cultures for mycoplasmas can be performed and joint destruction minimized.
我们描述了一名患有低丙种球蛋白血症的男性，他因解脲脲原体感染而患有侵蚀性少关节化脓性关节炎。他的临床病程因皮下脓肿而复杂化。多次滑膜培养均为阴性，直到最后进行了针对支原体的特异性培养。在低丙种球蛋白血症患者中不能依赖血清学诊断，因为他们不会产生明显的抗体反应。这凸显了高度怀疑支原体作为该人群化脓性关节炎病原体的临床重要性，以及尽早与微生物实验室沟通，以便能够进行针对支原体的适当培养并将关节破坏降至最低。
