Department of Pediatric Endocrinology, Diabetology and Metabolism, Inselspital, Bern University Children's Hospital, University of Bern, Bern, Switzerland.
Department of BioMedical Research, University of Bern, Bern, Switzerland.
Acta Paediatr. 2021 Aug;110(8):2424-2429. doi: 10.1111/apa.15814. Epub 2021 Mar 2.
This study assessed lifestyle-related risk factors for cardiovascular disease in young women with Turner syndrome.
In 2012, we sent a questionnaire to women with Turner syndrome aged ≥18 years and living in Switzerland with questions on socio-demographic and medical data as well as health behaviour. We compared the reported lifestyle with that of women from the Swiss Health Survey 2012, a representative survey of the general population.
Fifty-seven per cent (45/79) of women with Turner syndrome answered the questionnaire (mean age: 24 years). Eighty per cent (36/45) had never smoked compared with 58% (1156/1972) of the general population (p < 0.01). Women with Turner syndrome engaged less often in binge drinking (34% vs. 71%) (p < 0.001), but consumed alcohol equally often as the general population (p = 0.327). They performed sports as often as the general population (p = 0.34), but only one quarter (11/45) of women with Turner syndrome adhered to official physical activity recommendations.
Although most women with Turner syndrome had a healthy lifestyle, only a minority had sufficient physical activity. Paediatricians should promote structured physical activity in girls with Turner syndrome from early childhood onwards to reduce their cardiovascular risk in adulthood and to increase long-term health-related quality of life.
本研究旨在评估特纳综合征年轻女性心血管疾病的生活方式相关危险因素。
2012 年，我们向瑞士居住的年龄≥18 岁的特纳综合征女性发送了一份问卷，内容涉及社会人口学和医学数据以及健康行为。我们将报告的生活方式与瑞士健康调查 2012 年的生活方式进行了比较，后者是一项针对一般人群的代表性调查。
57%（45/79）的特纳综合征女性回答了问卷（平均年龄：24 岁）。80%（36/45）的女性从未吸烟，而普通人群中这一比例为 58%（1156/1972）（p<0.01）。特纳综合征女性暴饮的情况较少（34%对 71%）（p<0.001），但与普通人群饮酒量相当（p=0.327）。她们参加体育活动的频率与普通人群相当（p=0.34），但只有四分之一（11/45）的特纳综合征女性符合官方体育活动建议。
尽管大多数特纳综合征女性的生活方式健康，但只有少数人有足够的体力活动。儿科医生应从儿童早期开始，在特纳综合征女孩中促进有组织的体育活动，以降低她们成年后患心血管疾病的风险，并提高长期与健康相关的生活质量。
