Trevisan Lucia, Kocsis Istvan, Hunter Christopher A
Department of Chemistry, University of Cambridge, , Lensfield Road, Cambridge, CB2 1EW, UK.
Chem Commun (Camb). 2021 Mar 1;57(17):2196-2198. doi: 10.1039/d0cc08322d.
Transmission of chemical signals across lipid bilayer membranes can be achieved using membrane-anchored molecules, where molecular motion across the bilayer is controlled by switching the polarity of two different head groups. An external redox signal delivered by ascorbic acid was used to trigger membrane translocation in a synthetic transduction system.
通过使用膜锚定分子,可以实现化学信号在脂质双分子层膜上的传递,其中双分子层上的分子运动通过切换两种不同头部基团的极性来控制。在一个合成转导系统中,使用由抗坏血酸传递的外部氧化还原信号来触发膜易位。