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利妥昔单抗与低剂量霉酚酸酯治疗儿童和青年成人激素依赖型肾病综合征复发的随机临床试验

Rituximab vs Low-Dose Mycophenolate Mofetil in Recurrence of Steroid-Dependent Nephrotic Syndrome in Children and Young Adults: A Randomized Clinical Trial.

作者信息

Ravani Pietro, Lugani Francesca, Drovandi Stefania, Caridi Gianluca, Angeletti Andrea, Ghiggeri Gian Marco

机构信息

Division of Nephrology, University of Calgary, Calgary, Alberta, Canada.

Division of Nephrology, Dialysis and Transplantation, Istituto Giannina Gaslini IRCCS, Genoa, Italy.

出版信息

JAMA Pediatr. 2021 Jun 1;175(6):631-632. doi: 10.1001/jamapediatrics.2020.6150.

Abstract

This randomized clinical trial examines the superiority of a single dose of rituximab vs low-dose mycophenolate mofetil in preventing the recurrence of steroid-dependent nephrotic syndrome in children and young adults.

摘要

这项随机临床试验旨在检验单剂量利妥昔单抗与低剂量霉酚酸酯在预防儿童和青年类固醇依赖型肾病综合征复发方面的优越性。

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