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撤回:MicroRNA-498 通过靶向 MDM2 介导 PPARγ 泛素化来干扰结肠癌的发生和侵袭。

RETRACTED: MicroRNA-498 disturbs the occurrence and aggression of colon cancer through targeting MDM2 to mediate PPARγ ubiquitination.

机构信息

Department of Interventional Treatment, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin 300060, China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin 300060, China; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.

Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin 300060, China; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China; Department of Hepatobiliary Surgery, Liver Cancer Center, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China; National Clinical Research Center for Cancer, Tianjin 300060, China.

出版信息

Life Sci. 2021 Jul 15;277:119225. doi: 10.1016/j.lfs.2021.119225. Epub 2021 Feb 19.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of this article that shares several characteristics with other articles in the eyebrow family of publications, tabulated here (https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0). In addition, Fig. 5A appears to show a digital composition of xenografted tumors. The journal requested the corresponding author comment on these concerns and provide the raw data. However the authors were not able to satisfactorily fulfil this request and therefore the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅爱思唯尔关于文章撤回的政策 (http://www.elsevier.com/locate/withdrawalpolicy)。应主编要求,本文已被撤回。人们对这篇文章的可靠性提出了质疑,该文章与眉家族出版物中的其他几篇文章有相似之处,这里列出了这些文章(https://docs.google.com/spreadsheets/d/149EjFXVxpwkBXYJOnOHb6RhAqT4a2llhj9LM60MBffM/edit#gid=0)。此外,图 5A 似乎显示了异种移植肿瘤的数字合成。期刊要求通讯作者对这些问题发表评论并提供原始数据。然而,作者未能令人满意地完成这一请求,因此主编决定撤回这篇文章。

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