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撤回:KDM5B 介导的 microRNA-448 上调通过抑制 TGIF1 来抑制甲状腺乳头状癌细胞的进展并减缓肿瘤生长。

RETRACTED: KDM5B-mediated microRNA-448 up-regulation restrains papillary thyroid cancer cell progression and slows down tumor growth via TGIF1 repression.

机构信息

Senile endocrinology, Xiangya Hospital Central South University, Changsha 410008, Hunan, China.

Senile endocrinology, Xiangya Hospital Central South University, Changsha 410008, Hunan, China.

出版信息

Life Sci. 2020 Jun 1;250:117519. doi: 10.1016/j.lfs.2020.117519. Epub 2020 Mar 5.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the Editor-in-Chief. Concern was raised about the reliability of the Transwell assay results shown in Figures 3G, 6F, and 7F, which appear to contain image similarities within some of the panels, as detailed here: https://pubpeer.com/publications/7680482DF471CF3FADB2D14154BCFF and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. In addition, several suspected image similarities were detected within the whole brain images in Figure 7I, and within the Transwell assays of Figure 7G. The journal requested the corresponding author comment on these concerns and provide the raw data. However, the authors were not able to satisfactorily fulfill this request and therefore the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅 Elsevier 关于文章撤回的政策 (http://www.elsevier.com/locate/withdrawalpolicy)。应主编的要求,撤回了这篇文章。对图 3G、6F 和 7F 中显示的 Transwell 测定结果的可靠性表示关注,这些结果似乎在某些面板中存在图像相似性,详细信息如下:https://pubpeer.com/publications/7680482DF471CF3FADB2D14154BCFF 和这里:https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249。此外,在图 7I 中的全脑图像中以及在图 7G 中的 Transwell 测定中检测到几个疑似图像相似性。期刊要求通讯作者对这些问题发表评论并提供原始数据。然而,作者无法令人满意地满足这一要求,因此主编决定撤回这篇文章。

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