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职业治疗与物理治疗与髋或膝关节置换术后处方阿片类药物使用时间的关系:一项对医疗保险参保者的回顾性队列研究。

Association of Occupational and Physical Therapy With Duration of Prescription Opioid Use After Hip or Knee Arthroplasty: A Retrospective Cohort Study of Medicare Enrollees.

机构信息

Division of Rehabilitation Sciences, School of Health Professions, University of Texas Medical Branch, Galveston, TX.

Department of Preventive Medicine and Community Health, University of Texas Medical Branch, Galveston, TX.

出版信息

Arch Phys Med Rehabil. 2021 Jul;102(7):1257-1266. doi: 10.1016/j.apmr.2021.01.086. Epub 2021 Feb 19.

Abstract

OBJECTIVE

To establish whether nonpharmacologic interventions, such as occupational and physical therapy, were associated with a shorter duration of prescription opioid use after hip or knee arthroplasty.

DESIGN

This retrospective cohort study used data from a national 5% Medicare sample database between January 1, 2010 and December 31, 2015.

SETTING

Home health or outpatient.

PARTICIPANTS

Adults 66 years or older with an inpatient total hip (n=4272) or knee (n=9796) arthroplasty (N=14,068).

INTERVENTIONS

We dichotomized patients according to whether they had received any nonpharmacologic pain intervention within 1 year after hospital discharge (eg, occupational or physical therapy evaluation). Using Cox proportional hazards, we treated exposure to nonpharmacologic interventions as time dependent to determine if skilled therapy was associated with duration of opioid use.

MAIN OUTCOME MEASURES

Duration of prescription opioid use.

RESULTS

Median time to begin nonpharmacologic interventions was 91 days (95% confidence interval [CI], 74-118d) for hip and 27 days (95% CI, 27-28d) for knee arthroplasty. Median time to discontinue prescription opioids was 16 days (hip: 95% CI, 15-16d) and 30 days (knee: 95% CI, 29-31d). Nonpharmacologic interventions delivered with home health increased the likelihood of discontinuing opioids after hip (hazard ratio [HR], 1.15; 95% CI, 1.01-1.30) and knee (HR, 1.10; 95% CI, 1.03-1.17) arthroplasty. A sensitivity analysis found these estimates to be robust and conservative.

CONCLUSIONS

Occupational and physical therapy with home health was associated with a shorter duration of prescription opioid use after hip and knee arthroplasty. Occupational and physical therapy can address pain and sociobehavioral factors associated with postsurgical opioid use.

摘要

目的

确定非药物干预措施(如职业治疗和物理治疗)是否与髋关节或膝关节置换术后处方类阿片药物使用时间缩短有关。

设计

本回顾性队列研究使用了 2010 年 1 月 1 日至 2015 年 12 月 31 日期间全国 5%医疗保险样本数据库的数据。

设置

家庭保健或门诊。

参与者

年龄在 66 岁及以上的髋关节(n=4272)或膝关节(n=9796)置换术(n=14068)的住院患者。

干预措施

我们根据患者在出院后 1 年内是否接受任何非药物性疼痛干预(如职业治疗或物理治疗评估)将患者分为两类。使用 Cox 比例风险模型,我们将接受非药物性干预的情况视为时间依赖性因素,以确定熟练治疗是否与阿片类药物使用时间长短有关。

主要观察指标

处方类阿片药物使用时间。

结果

髋关节置换术开始非药物性干预的中位数时间为 91 天(95%置信区间[CI],74-118d),膝关节置换术为 27 天(95%CI,27-28d)。停止使用处方类阿片药物的中位数时间为 16 天(髋关节:95%CI,15-16d)和 30 天(膝关节:95%CI,29-31d)。家庭保健中提供的非药物性干预增加了髋关节(风险比[HR],1.15;95%CI,1.01-1.30)和膝关节(HR,1.10;95%CI,1.03-1.17)置换术后停止使用阿片类药物的可能性。敏感性分析发现这些估计结果稳健且保守。

结论

髋关节和膝关节置换术后,家庭保健中提供的职业治疗和物理治疗与处方类阿片药物使用时间缩短有关。职业治疗和物理治疗可以解决与术后阿片类药物使用相关的疼痛和社会行为因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6adc/8263496/675cceedc75f/nihms-1681703-f0001.jpg

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