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[Spontaneous course of Wegener's granulomatosis].

作者信息

Adam O, Wiesinger H

机构信息

Medizinische Poliklinik der Universität München.

出版信息

Klin Wochenschr. 1988 Mar 1;66(5):181-6. doi: 10.1007/BF01728194.

DOI:10.1007/BF01728194
PMID:3361797
Abstract

Two cases of Wegener's granulomatosis are reported. During the 5 and 9 years course of the disease complete remissions and the disappearance of pulmonary opacities were found without specific treatment. Since 1970 cytotoxic drugs, e.g. cyclophosphamide, are frequently used for the treatment of Wegener's granulomatosis. The evaluation of the follow-up showed in these patients that in most cases the side-effects of the therapy, and not the primary disease, limited the life-expectancy. This especially applies for patients with mild forms of Wegener's granulomatosis, in which the initiation of a cytotoxic therapy should carefully be evaluated.

摘要

相似文献

1
[Spontaneous course of Wegener's granulomatosis].
Klin Wochenschr. 1988 Mar 1;66(5):181-6. doi: 10.1007/BF01728194.
2
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本文引用的文献

1
Wegener's granulomatosis.韦格纳肉芽肿病
Am J Med. 1954 Aug;17(2):168-79. doi: 10.1016/0002-9343(54)90255-7.
2
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Laryngol Rhinol Otol (Stuttg). 1981 May;60(5):241-4.
3
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.韦格纳肉芽肿病：85例患者21年的前瞻性临床与治疗经验
Ann Intern Med. 1983 Jan;98(1):76-85. doi: 10.7326/0003-4819-98-1-76.
4
The use of alkylating agents in the treatment of Wegener's granulomatosis.烷化剂在韦格纳肉芽肿治疗中的应用。
Ann Intern Med. 1967 Aug;67(2):393-8. doi: 10.7326/0003-4819-67-2-393.
5
Wegener's granulomatosis: observations on treatment with antimicrobial agents.韦格纳肉芽肿：抗菌药物治疗观察
Mayo Clin Proc. 1985 Jan;60(1):27-32. doi: 10.1016/s0025-6196(12)65279-3.
6
Autoantibodies against neutrophils and monocytes: tool for diagnosis and marker of disease activity in Wegener's granulomatosis.抗中性粒细胞和单核细胞自身抗体：韦格纳肉芽肿病的诊断工具及疾病活动标志物
Lancet. 1985 Feb 23;1(8426):425-9. doi: 10.1016/s0140-6736(85)91147-x.