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多巴胺能和神经营养遗传多态性调节内隐性别-科学刻板印象。

Dopaminergic and neurotrophic genetic polymorphisms modulate the implicit gender-science stereotype.

机构信息

CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing, China.

CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.

出版信息

Psych J. 2021 Jun;10(3):364-373. doi: 10.1002/pchj.428. Epub 2021 Feb 22.

DOI:10.1002/pchj.428
PMID:33619907
Abstract

Genetic approaches to both the gender-science stereotype and implicit social cognition have received increasing attention in recent years. We explored whether single nucleotide polymorphisms (SNPs) in dopaminergic and neurotrophic systems (i.e., COMT, BDNF genotypes) explain variations in the implicit gender-science stereotype. We genotyped 413 adolescents and assessed their implicit gender-science stereotype with the Implicit Association Test. Replication on a subsample (N = 312) was conducted 2 years later. Results showed that SNP-level variations within the COMT and BDNF genes were consistently associated with the implicit gender-science stereotype in both investigations. These findings suggest that variants in the COMT and BDNF genes may contribute to the variation of implicit gender-science stereotype.

摘要

近年来,遗传方法在性别科学刻板印象和内隐社会认知方面受到了越来越多的关注。我们探讨了多巴胺能和神经营养系统(即 COMT、BDNF 基因型)中的单核苷酸多态性(SNPs)是否可以解释内隐性别科学刻板印象的变化。我们对 413 名青少年进行了基因分型,并使用内隐联想测验评估了他们的内隐性别科学刻板印象。两年后在一个子样本(N=312)上进行了复制。结果表明,在这两项研究中,COMT 和 BDNF 基因内的 SNP 水平变化与内隐性别科学刻板印象始终相关。这些发现表明,COMT 和 BDNF 基因中的变异可能对内隐性别科学刻板印象的变化有贡献。

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