Glaucoma Department, Beirut Eye Clinic, Beirut, Lebanon.
Vitreoretinal Department, Beirut Eye & ENT Specialist Hospital, Beirut, Lebanon ; and.
Retina. 2021 Jul 1;41(7):1403-1406. doi: 10.1097/IAE.0000000000003056.
BACKGROUND/PURPOSE: To evaluate the prevalence and extent of vitreous cortex remnants (VCR) on the surface of the retina in eyes with primary rhegmatogenous retinal detachment (RRD) and posterior vitreous detachment.
Triamcinolone acetonide was injected in the vitreous cavity of 100 consecutive cases of acute primary RRD undergoing pars plana vitrectomy. A multivariate regression analysis was performed to determine any association between the presence and pattern of stained VCR on the surface of the retina and the following variables: age, diabetes, axial length, phakic status, extent of RRD, and macular status.
Vitreous cortex remnants were found in 42 eyes. These were focal in eight eyes and diffuse in 34 eyes. Age was the only strong and independent risk factor associated with the presence of VCR (P = 0.0019). Age (P < 0.0001), axial length (P = 0.0037), and phakia (P = 0.01) were independent risk factors associated with the diffuse pattern. Neither diabetes, extent of RRD, nor macular status were significant risk factors for the presence or extent of VCR.
Older patients with primary RRD and posterior vitreous detachment seem to be at a higher risk of having diffuse VCR. Further studies are needed to investigate the relevance of VCR in the pathogenesis, progression and treatment of RD.
背景/目的:评估原发性孔源性视网膜脱离(RRD)伴玻璃体后脱离眼表面玻璃体皮质残留(VCR)的发生率和范围。
对 100 例接受经睫状体平坦部玻璃体切除术的急性原发性 RRD 连续病例,玻璃体腔注射曲安奈德。采用多元回归分析,确定视网膜表面染色 VCR 的存在和模式与以下变量之间的任何关联:年龄、糖尿病、眼轴长度、晶状体状态、RRD 程度和黄斑状态。
42 只眼发现玻璃体皮质残留。8 只眼为局灶性,34 只眼为弥漫性。年龄是唯一与 VCR 存在相关的强独立危险因素(P = 0.0019)。年龄(P < 0.0001)、眼轴长度(P = 0.0037)和白内障(P = 0.01)是弥漫性模式的独立危险因素。糖尿病、RRD 程度和黄斑状态均不是 VCR 存在或程度的显著危险因素。
原发性 RRD 伴玻璃体后脱离的老年患者似乎有更高的弥漫性 VCR 风险。需要进一步研究以探讨 VCR 在 RD 的发病机制、进展和治疗中的相关性。