Dierickx K, Vandesande F
Cell Tissue Res. 1977 Oct 21;184(1):15-27. doi: 10.1007/BF00220524.
The human hypothalamic-neurohypophysial hormone-producing nuclei were investigated with the unlabeled antibody peroxidase-antiperoxidase complex (PAP) technique at the light microscopic level. The size, shape and location of the supraoptic, paraventricular, accessory supraoptic and suprachiasmatic nuclei were determined. It was demonstrated in the human hypothalamus, as well as in the hypothalamus of other mammals, that vasopressin and oxytocin are synthesized in separate neurons. In each of the nuclei of the magnocellular neurosecretory system, the distribution, ratios and structural features of the vasopressinergic and oxytocinergic neurons were determined. It was shown that the human suprachiasmatic nuclei contain numerous neurophysin-vasopressin-producing neurons.
采用非标记抗体过氧化物酶-抗过氧化物酶复合物（PAP）技术，在光学显微镜水平对人下丘脑-神经垂体激素产生核团进行了研究。确定了视上核、室旁核、视上副核和视交叉上核的大小、形状和位置。研究表明，在人类下丘脑以及其他哺乳动物的下丘脑中，血管加压素和催产素是在不同的神经元中合成的。在大细胞神经分泌系统的每个核团中，确定了血管加压素能神经元和催产素能神经元的分布、比例和结构特征。结果显示，人类视交叉上核含有大量产生神经垂体素-血管加压素的神经元。
