Kawata M, Sano Y
Anat Embryol (Berl). 1982;165(2):151-67. doi: 10.1007/BF00305474.
The hypothalamic oxytocin and vasopressin neurons of the monkey, Macaca fuscata, were demonstrated in Golgi-like images by a modified immunoperoxidase method. The magnocellular oxytocin and vasopressin neurons were distributed mainly in the supraoptic and paraventricular nuclei. In addition to these main nuclei, both types of magnocellular neurons were found in the accessory supraoptic nucleus, the periventricular and perifornical areas, the nucleus of the stria terminalis, the lateral hypothalamic area, and the pars interna of the globus pallidus. Magnocellular oxytocin neurons were seen immediately ventral to the anterior commissure, and parvocellular vasopressin neurons were localized in the medial portion of the suprachiasmatic nucleus. The preferential distribution of the oxytocin and vasopressin neurons was recognized not only in the supraoptic and paraventricular nuclei, but also in other areas. In all areas observed, the cytological difference between the oxytocin and vasopressin neurons could be identified. The area of the perikarya of the vasopressin neurons was determined to be larger than that of the oxytocin neurons. Most of the axons of the oxytocin neurons issued from the perikarya, while the axons of the vasopressin neurons originated in most cases from the thick proximal dendrites. These results show that the oxytocin and vasopressin neurons are distributed in areas much broader than has hitherto been assumed, and that these two peptidergic neurons can be definitely differentiated morphologically as well as functionally.
通过改良免疫过氧化物酶法，在类高尔基体图像中显示了猕猴（Macaca fuscata）下丘脑的催产素和加压素神经元。大细胞性催产素和加压素神经元主要分布在视上核和室旁核。除了这些主要核团外，在视上核附属核、室周和穹窿周区域、终纹床核、下丘脑外侧区以及苍白球内侧部均发现了这两种类型的大细胞神经元。大细胞性催产素神经元见于前连合正腹侧，小细胞性加压素神经元定位于视交叉上核的内侧部分。不仅在视上核和室旁核，在其他区域也可识别出催产素和加压素神经元的优先分布。在所有观察区域，均可识别出催产素和加压素神经元之间的细胞学差异。确定加压素神经元的胞体面积大于催产素神经元。催产素神经元的轴突大多从胞体发出，而加压素神经元的轴突大多起源于粗大的近端树突。这些结果表明，催产素和加压素神经元的分布区域比迄今所认为的要广泛得多，并且这两种肽能神经元在形态和功能上均可明确区分。
