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双甲状腺异位:病例图片系列及文献综述

Dual thyroid ectopia: A pictorial case series and review of literature.

作者信息

Kumar Ashok, Singhal Tejasvini, Krishna Sai Mohan, Narayan Manishi L

机构信息

Department of Nuclear Medicine, All India Institute of Medical Sciences, Rishikesh, Uttrakhanad, India.

Department of Nuclear Medicine, Sri Venkateshwara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India.

出版信息

World J Nucl Med. 2020 Sep 14;19(4):336-340. doi: 10.4103/wjnm.WJNM_44_20. eCollection 2020 Oct-Dec.

Abstract

Ectopic thyroid (ET) is a developmental anomaly of the thyroid gland with the presence of thyroid tissue at sites other than the normal cervical location anterior to second and third tracheal ring due to abnormal migration of the gland. It may be found along the path of descent of the developing thyroid primordium from the foramen caecum to the isthmus of the thyroid and up to the base of the diaphragm. Dual thyroid ectopia, where ET tissue is simultaneously present at two different abnormal locations, is a very rare developmental defect. Only a few cases have been reported worldwide. ET is predominantly seen in females and during puberty when the hormonal demand is high. Patients with ET may remain asymptomatic or present with swelling in the neck, symptoms such as dysphagia, dysphonia, dyspnea, and features of hypothyroidism. The diagnosis is usually made on clinical examination, laboratory tests, imaging studies, and cytology. Careful clinical evaluation is essential as ET may be the only functioning thyroid tissue. Thyroid scintigraphy is an important imaging tool and the gold standard for the diagnosis of ET tissue, as it has high sensitivity and specificity. Early and accurate diagnosis of ET is essential to start hormone replacement and avoid unnecessary surgery. The authors report here a series of four patients with dual ET tissue, diagnosed on thyroid scintigraphy.

摘要

异位甲状腺(ET)是一种甲状腺发育异常,由于甲状腺腺体异常迁移,甲状腺组织出现在正常颈部位置(气管第二和第三软骨环前方)以外的部位。它可能出现在发育中的甲状腺原基从盲孔到甲状腺峡部直至膈肌底部的下降路径上。双发性甲状腺异位是指ET组织同时出现在两个不同的异常位置,这是一种非常罕见的发育缺陷。全球仅报道了少数病例。ET主要见于女性以及激素需求旺盛的青春期。ET患者可能无症状,或出现颈部肿胀、吞咽困难、声音嘶哑、呼吸困难等症状以及甲状腺功能减退的表现。诊断通常基于临床检查、实验室检查、影像学检查和细胞学检查。由于ET可能是唯一有功能的甲状腺组织,仔细的临床评估至关重要。甲状腺闪烁扫描是诊断ET组织的重要影像学工具和金标准,因为它具有高敏感性和特异性。早期准确诊断ET对于开始激素替代治疗和避免不必要的手术至关重要。作者在此报告了一系列经甲状腺闪烁扫描诊断为双发性ET组织的4例患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/affa/7875023/f1352f2972e4/WJNM-19-336-g001.jpg

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