Hussain Riffat Parveen, Mahmood Tariq
Department of Radiology, PET-CT, Jinnah Postgraduate Medical Center, Karachi, Pakistan.
World J Nucl Med. 2020 Jul 22;19(4):438-440. doi: 10.4103/wjnm.WJNM_7_20. eCollection 2020 Oct-Dec.
Scanning oncological patients with F-fluorodeoxyglucose (F-FDG) for their disease staging, evaluation of treatment response, and monitoring/management has become a standard of care. The use of the radioactive fluorine in the FDG molecule helps establish cell/tissue lines high on glucose consumption and hence metabolically active. Abnormalities are detected on the scan as areas of increased uptake. However, these areas of increased (hot) uptakes do not necessarily translate into a pathological finding. A comprehensive knowledge of the uptakes of the tracer and the potential "pitfalls" that may be associated with them should be known and kept in mind during scan reading. One such pitfall is the "hot clot" or "pulmonary emboli," and we report two such cases encountered at our setup and discuss their causes and how they should be identified and avoided.
使用氟代脱氧葡萄糖(F-FDG)对肿瘤患者进行扫描以进行疾病分期、评估治疗反应以及监测/管理已成为一种标准治疗方法。FDG分子中放射性氟的使用有助于确定葡萄糖消耗高因而代谢活跃的细胞/组织系。扫描时,摄取增加的区域被检测为异常。然而,这些摄取增加(热)的区域不一定意味着存在病理发现。在解读扫描结果时,应了解并牢记示踪剂摄取情况以及可能与之相关的潜在“陷阱”。其中一个陷阱就是“热血栓”或“肺栓塞”,我们报告在我们机构遇到的两例此类病例,并讨论其原因以及应如何识别和避免。