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F-氟脱氧葡萄糖热栓子

The hot embolus of F-fluorodeoxyglucose.

作者信息

Hussain Riffat Parveen, Mahmood Tariq

机构信息

Department of Radiology, PET-CT, Jinnah Postgraduate Medical Center, Karachi, Pakistan.

出版信息

World J Nucl Med. 2020 Jul 22;19(4):438-440. doi: 10.4103/wjnm.WJNM_7_20. eCollection 2020 Oct-Dec.

DOI:10.4103/wjnm.WJNM_7_20
PMID:33623519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7875025/
Abstract

Scanning oncological patients with F-fluorodeoxyglucose (F-FDG) for their disease staging, evaluation of treatment response, and monitoring/management has become a standard of care. The use of the radioactive fluorine in the FDG molecule helps establish cell/tissue lines high on glucose consumption and hence metabolically active. Abnormalities are detected on the scan as areas of increased uptake. However, these areas of increased (hot) uptakes do not necessarily translate into a pathological finding. A comprehensive knowledge of the uptakes of the tracer and the potential "pitfalls" that may be associated with them should be known and kept in mind during scan reading. One such pitfall is the "hot clot" or "pulmonary emboli," and we report two such cases encountered at our setup and discuss their causes and how they should be identified and avoided.

摘要

使用氟代脱氧葡萄糖(F-FDG)对肿瘤患者进行扫描以进行疾病分期、评估治疗反应以及监测/管理已成为一种标准治疗方法。FDG分子中放射性氟的使用有助于确定葡萄糖消耗高因而代谢活跃的细胞/组织系。扫描时,摄取增加的区域被检测为异常。然而,这些摄取增加(热)的区域不一定意味着存在病理发现。在解读扫描结果时,应了解并牢记示踪剂摄取情况以及可能与之相关的潜在“陷阱”。其中一个陷阱就是“热血栓”或“肺栓塞”,我们报告在我们机构遇到的两例此类病例,并讨论其原因以及应如何识别和避免。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308f/7875025/182b2eb5ddb9/WJNM-19-438-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308f/7875025/45f4b956a890/WJNM-19-438-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308f/7875025/182b2eb5ddb9/WJNM-19-438-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308f/7875025/45f4b956a890/WJNM-19-438-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/308f/7875025/182b2eb5ddb9/WJNM-19-438-g002.jpg

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Indian J Nucl Med. 2017 Oct-Dec;32(4):359-360. doi: 10.4103/ijnm.IJNM_68_17.
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Pitfalls and Artifacts in the Use of PET/CT in Oncology Imaging.PET/CT在肿瘤成像中的陷阱与伪影
Semin Nucl Med. 2015 Nov;45(6):481-99. doi: 10.1053/j.semnuclmed.2015.02.006.
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18F-FDG PET/CT lung 'focalities' without coregistered CT findings: an interpretative clinical dilemma.18F-FDG PET/CT检查发现肺部有“局灶性病变”但CT未发现相应表现:临床诊断的两难困境
Nucl Med Commun. 2015 Apr;36(4):334-9. doi: 10.1097/MNM.0000000000000261.
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Hot-clot artifacts in the lung parenchyma on F-18 fluorodeoxyglucose positron emission tomography/CT due to faulty injection techniques: two case reports.因注射技术失误导致的 F-18 氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(F-18 fluorodeoxyglucose positron emission tomography/CT)肺实质内热凝块伪影:两例报告
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