Heiman-Patterson T, Martino C, Rosenberg H, Fletcher J, Tahmoush A
Department of Neurology, Hahnemann University Hospital, Philadelphia, PA 19102.
Neurology. 1988 May;38(5):810-2. doi: 10.1212/wnl.38.5.810.
We report a family in which two sisters with myotonia congenita (MyC) were referred for malignant hyperthermia (MH) evaluation after each developed muscle rigidity with anesthesia. Halothane contracture testing of skeletal muscle in both was consistent with MH susceptibility. A third sister without clinical evidence of MyC was negative on contracture testing. These results suggest an association between MyC and MH susceptibility.
我们报告了一个家族，其中两名患有先天性肌强直（MyC）的姐妹在麻醉后均出现肌肉强直，随后被转诊进行恶性高热（MH）评估。两人的骨骼肌氟烷挛缩试验结果均与MH易感性相符。第三名无MyC临床证据的姐妹挛缩试验结果为阴性。这些结果提示MyC与MH易感性之间存在关联。
