Aijaz Zobia, Durrani Hafiza M, Iftikhar Pulwasha, Khenhrani Raja Ram, FaisalUddin Mohammed
Internal Medicine, Dow University of Health and Sciences, Karachi, PAK.
Pediatrics, Dr. Ruth Pfau Civil Hospital Karachi/Dow University of Health and Sciences, Karachi, PAK.
Cureus. 2021 Jan 20;13(1):e12799. doi: 10.7759/cureus.12799.
Neuroblastoma is the most common childhood malignancy arising from the sympathetic neuroblast cells. The most common sites of origin are the adrenal glands and paravertebral regions. However, the involvement of the heart is a rare occurrence in adolescents. Here, we report a case of a 12-year-old male child who was misdiagnosed as a case of cardiac myxoma on initial presentation. Following surgical resection and histological examination, neuroblastoma was revealed. This case report highlights the differential diagnosis for the cardiac mass in an adolescent with an unknown primary origin and also the importance of tissue histopathology for the diagnosis and management of neuroblastoma.
神经母细胞瘤是起源于交感神经母细胞的最常见儿童恶性肿瘤。最常见的起源部位是肾上腺和椎旁区域。然而,心脏受累在青少年中较为罕见。在此,我们报告一例12岁男性儿童,初诊时被误诊为心脏黏液瘤。经手术切除及组织学检查后,确诊为神经母细胞瘤。本病例报告强调了对原发灶不明的青少年心脏肿块的鉴别诊断,以及组织病理学在神经母细胞瘤诊断和治疗中的重要性。