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4个月大时进行常规疫苗接种后出现的全身性血管炎和暴发性肝炎。

Pan-vasculitis and fulminant hepatitis following routine vaccination at the age of 4 months.

作者信息

Awad Mohammad Hosny, El-Hawary Amany, Sawah Gehan, Nasef Nehad

机构信息

Department of Pediatrics, Faculty of Medicine, University of Mansoura, Mansoura, Egypt.

出版信息

Clin Exp Vaccine Res. 2021 Jan;10(1):78-80. doi: 10.7774/cevr.2021.10.1.78. Epub 2021 Jan 31.

Abstract

Vaccines are known to have side effects, most of which are tolerable. Vasculitis following vaccination is reported and has various modes of presentation. We report a 4-month-old girl presented with an unusual presentation of fulminant hepatitis, pan vasculitis, and diffuse body aneurysms following routine immunization diagnosed by echocardiography and computed tomography angiogram. It is important to be aware of different possible adverse effects following vaccines and their different modes of presentation as well as possible treatments such as intravenous immunoglobulins and high dose methylprednisolone.

摘要

疫苗已知会有副作用,其中大多数是可以耐受的。接种疫苗后发生血管炎的情况已有报道,且有多种表现形式。我们报告了一名4个月大的女孩,在常规免疫接种后出现了暴发性肝炎、全身性血管炎和弥漫性身体动脉瘤的不寻常表现,通过超声心动图和计算机断层血管造影确诊。了解疫苗接种后不同的可能不良反应及其不同表现形式,以及诸如静脉注射免疫球蛋白和大剂量甲基强的松龙等可能的治疗方法非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d356/7892943/e0b4764b6f54/cevr-10-78-g001.jpg

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