• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新冠大流行的另一个前线。

Another front in COVID-19's perfect storm.

机构信息

Versiti Blood Research Institute.

Medical College of Wisconsin.

出版信息

Blood. 2021 Feb 25;137(8):1006-1007. doi: 10.1182/blood.2020010459.

DOI:10.1182/blood.2020010459
PMID:33630053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7906012/
Abstract

In this issue of , Althaus et al identify circulating procoagulant platelets as a novel biomarker of COVID-19 disease severity and present provocative in vitro findings demonstrating that antibodies induced in response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can initiate procoagulant platelet formation.

摘要

在本期 中,Althaus 等人将循环促凝血小板确定为 COVID-19 疾病严重程度的新型生物标志物,并提出了一些有争议的体外研究结果,表明针对严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)产生的抗体可以引发促凝血小板形成。

相似文献

1
Another front in COVID-19's perfect storm.新冠大流行的另一个前线。
Blood. 2021 Feb 25;137(8):1006-1007. doi: 10.1182/blood.2020010459.
2
In the Path of the Storm: North Carolina's Response to COVID-19's Impact on Historically Marginalized Populations.在风暴的路径上:北卡罗来纳州对新冠疫情对历史上被边缘化人群影响的应对措施
N C Med J. 2021 Jul-Aug;82(4):276-277. doi: 10.18043/ncm.82.4.276.
3
Prediction of severe adverse events, modes of action and drug treatments for COVID-19's complications.预测 COVID-19 并发症的严重不良事件、作用模式和药物治疗。
Sci Rep. 2021 Oct 21;11(1):20864. doi: 10.1038/s41598-021-00368-6.
4
COVID-19's impact on bioanalytical labs.COVID-19 对生物分析实验室的影响。
Bioanalysis. 2021 Aug;13(15):1169-1171. doi: 10.4155/bio-2021-0103. Epub 2021 Aug 10.
5
Mitigating COVID-19's impact on missed and delayed cancer diagnoses.减轻新冠疫情对癌症诊断延误和漏诊的影响。
Can Fam Physician. 2022 May;68(5):323-324. doi: 10.46747/cfp.6805323.
6
COVID-19's impact on the future of digital health technology in primary care.新冠疫情对初级医疗保健中数字健康技术未来的影响。
Fam Pract. 2021 Nov 24;38(6):845-847. doi: 10.1093/fampra/cmab081.
7
COVID-19's lost generation of unvaccinated children.新冠疫情下未接种疫苗的“迷失一代”儿童。
Lancet Glob Health. 2021 Mar;9(3):e250. doi: 10.1016/S2214-109X(20)30535-0. Epub 2021 Jan 6.
8
What do we know about covid-19's effects on the brain?我们对新冠病毒对大脑的影响了解多少?
BMJ. 2024 May 15;385:q897. doi: 10.1136/bmj.q897.
9
New Federal Guidance Says COVID-19's Long-term Effects Can Qualify as a Disability.新的联邦指导意见称,新冠病毒的长期影响可被认定为残疾。
JAMA Health Forum. 2021 Aug 3;2(8):e212820. doi: 10.1001/jamahealthforum.2021.2820.
10
Epilepsy and COVID-19's Double-Edged Sword: More Severe Disease and Delayed Epilepsy Care.癫痫与新冠疫情的双刃剑:更严重的疾病与癫痫护理延误
Neurology. 2022 May 10;98(19):779-780. doi: 10.1212/WNL.0000000000200367. Epub 2022 Mar 25.

引用本文的文献

1
Prothrombotic antibodies targeting the spike protein's receptor-binding domain in severe COVID-19.针对重症 COVID-19 中刺突蛋白受体结合域的促血栓形成抗体。
Blood. 2025 Feb 6;145(6):635-647. doi: 10.1182/blood.2024025010.
2
COVID-19 and renal infarct: To be or not to be on anticoagulation.新型冠状病毒肺炎与肾梗死:是否进行抗凝治疗
Clin Nephrol Case Stud. 2021 Nov 9;9:117-122. doi: 10.5414/CNCS110602. eCollection 2021.

本文引用的文献

1
Antibody-induced procoagulant platelets in severe COVID-19 infection.严重 COVID-19 感染中的抗体诱导的促凝血小板。
Blood. 2021 Feb 25;137(8):1061-1071. doi: 10.1182/blood.2020008762.
2
Prothrombotic autoantibodies in serum from patients hospitalized with COVID-19.COVID-19 住院患者血清中的促血栓形成自身抗体。
Sci Transl Med. 2020 Nov 18;12(570). doi: 10.1126/scitranslmed.abd3876. Epub 2020 Nov 2.
3
The Impact of COVID-19 Disease on Platelets and Coagulation.新型冠状病毒疾病对血小板和凝血的影响。
Pathobiology. 2021;88(1):15-27. doi: 10.1159/000512007. Epub 2020 Oct 13.
4
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.滤泡外 B 细胞反应与 COVID-19 中的中和抗体和发病相关。
Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7.
5
Kinetics of viral load and antibody response in relation to COVID-19 severity.病毒载量和抗体反应动力学与 COVID-19 严重程度的关系。
J Clin Invest. 2020 Oct 1;130(10):5235-5244. doi: 10.1172/JCI138759.
6
Platelet necrosis mediates ischemic stroke outcome in mice.血小板坏死介导小鼠缺血性脑卒中结局。
Blood. 2020 Feb 6;135(6):429-440. doi: 10.1182/blood.2019002124.
7
The mitochondrial calcium uniporter regulates procoagulant platelet formation.线粒体钙单向转运体调节促凝血小板的形成。
J Thromb Haemost. 2018 Nov;16(11):2315-2321. doi: 10.1111/jth.14284. Epub 2018 Oct 29.
8
Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia.中性粒细胞大聚集促进肠道缺血后广泛肺血栓形成。
Sci Transl Med. 2017 Sep 27;9(409). doi: 10.1126/scitranslmed.aam5861.
9
Procoagulant Platelets: Further Details but Many More Questions.促凝血小板:更多细节,但也有更多问题。
Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1596-1597. doi: 10.1161/ATVBAHA.117.309847.
10
Simultaneous engagement of thrombin and Fc gamma RIIA receptors results in platelets expressing high levels of procoagulant proteins.凝血酶和FcγRIIA受体的同时激活导致血小板表达高水平的促凝血蛋白。
J Lab Clin Med. 2001 Dec;138(6):393-402. doi: 10.1067/mlc.2001.120049.