Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, China.
Minim Invasive Ther Allied Technol. 2022 Apr;31(4):496-504. doi: 10.1080/13645706.2020.1864408. Epub 2021 Feb 25.
We systematically evaluated the difference in diagnostic accuracy, check time, and adverse effects between magnetically controlled capsule gastroscopy (MCCG) and conventional gastroscopy in patients with gastric disorders.
PubMed, Embase, Cochrane, CKNI and Wanfang Data were searched for studies dated prior to 30 January 2020. We used the QUADAS criteria for quality evaluation. We extracted the diagnostic rate, check time, and adverse events from the studies, then used STATA15.0 to calculate variables (sensitivity, specificity, positive likelihood ratio [LR], negative likelihood ratio [LR] and diagnostic odds ratio), draw forest plots and SROC curves, and completed sensitivity analysis.
A total of 278 titles were identified after an initial search and nine studies with 1,146 individuals were included in the analysis. The pooled sensitivity, specificity, LR and LR of MCCG in detecting gastric disorders were 90%, 92%, 10.6, and 0.11, respectively. A ROC curve was drawn with = 0.9060 and AUG = 0.96. The diagnostic odds ratio was 93.
No significant difference in diagnosis accuracy was demonstrated between MCCG and conventional gastroscopy. The MCCG had a longer check time than conventional gastroscopy and the adverse events occurrence rate was lower. MCCG is a convenient and reliable examination method for gastric diseases.
系统评价磁控胶囊胃镜（MCCG）与常规胃镜检查在胃部疾病患者中的诊断准确性、检查时间和不良反应差异。
检索 2020 年 1 月 30 日前发表的 PubMed、Embase、Cochrane、中国知网（CNKI）和万方数据库中的相关研究。采用 QUADAS 标准进行质量评价。从研究中提取诊断率、检查时间和不良反应等数据，采用 STATA15.0 计算变量（灵敏度、特异度、阳性似然比[LR]、阴性似然比[LR]和诊断比值比[DOR]），绘制森林图和 SROC 曲线，并进行敏感性分析。
初筛后共得到 278 个标题，分析纳入 9 项研究，共 1146 例患者。MCCG 诊断胃部疾病的汇总灵敏度、特异度、LR 和 LR 分别为 90%、92%、10.6 和 0.11。绘制 ROC 曲线，AUC = 0.9060，AUG = 0.96。DOR 为 93。
MCCG 与常规胃镜检查在诊断准确性方面无显著差异。MCCG 检查时间长于常规胃镜，不良反应发生率较低。MCCG 是一种方便、可靠的胃部疾病检查方法。
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