Department of Gastroenterology, Changhai Hospital, Second Military Medical Universtiy, National Clinical Research Center for Digestive Diseases, Shanghai, China.
Department of Gastroenterology, Changhai Hospital, Second Military Medical Universtiy, National Clinical Research Center for Digestive Diseases, Shanghai, China; Department of Gastroenterology, Anqing Municipal Hospital of Anhui Medical University, Anqing, China.
Dig Liver Dis. 2018 Oct;50(10):1041-1046. doi: 10.1016/j.dld.2018.04.013. Epub 2018 Apr 24.
Magnetically controlled capsule gastroscopy (MCCG) is a newly developed non-invasive method designed for gastric examination. Although favorable diagnostic accuracy has been reported, there is little if any data about its ability to diagnose gastric cancer.
To compare the detectability of superficial gastric neoplasia by MCCG and gastroscopy.
This study was a self-controlled comparison study. Ten subjects diagnosed with superficial gastric neoplasia and scheduled to undergo endoscopic submucosal dissection (ESD) at a tertiary hospital were prospectively invited for an MCCG examination. The diagnostic agreement of MCCG, ESD and pathology were compared, including location, size and endoscopic appearance of the lesions.
Of the 10 enrolled patients, 6 were confirmed as having early gastric cancer/high-grade intraepithelial neoplasia, 2 gastric low-grade intraepithelial neoplasia (LGIN), 1 tubular adenoma with LGIN and 1 neuroendocrine tumor. The per-patient and per-lesion sensitivities of MCCG for superficial gastric neoplasia detection were 100% and 91.7%. Location and size of the lesions were compared favorably to gastroscopy whilst one cardiac lesion was missed. Endoscopic appearances of these lesions observed on MCCG and EGD demonstrated good consistency. No adverse events were observed.
With good gastric preparation and careful examination of stomach, MCCG is able to detect superficial gastric neoplasms.
磁控胶囊胃镜（MCCG）是一种新开发的非侵入性胃检查方法。尽管已有报道称其具有良好的诊断准确性，但关于其诊断胃癌能力的数据却很少。
比较 MCCG 和胃镜对胃浅表性肿瘤的检出能力。
本研究为自身对照比较研究。前瞻性邀请 10 名在三级医院诊断为胃浅表性肿瘤并计划行内镜黏膜下剥离术（ESD）的患者接受 MCCG 检查。比较 MCCG、ESD 和病理的诊断一致性，包括病变的位置、大小和内镜表现。
10 名入组患者中，6 例被确认为早期胃癌/高级上皮内瘤变，2 例胃低级别上皮内瘤变（LGIN），1 例管状腺瘤伴 LGIN 和 1 例神经内分泌肿瘤。MCCG 对胃浅表性肿瘤的检出的患者检出率和病变检出率均为 100%和 91.7%。病变的位置和大小与胃镜相比具有较好的一致性，而有 1 个心脏病变被遗漏。MCCG 和 EGD 观察到的这些病变的内镜表现具有较好的一致性。未观察到不良事件。
在良好的胃准备和仔细的胃部检查下，MCCG 能够检测出胃浅表性肿瘤。
