[喹啉衍生物的辐射修饰效应]
[Radiation-modifying effect of quinoline derivatives].
作者信息
Vasin M V, Suvorov N N, Semenova L A, Il'ina G N
出版信息
Radiobiologiia. 1988 Mar-Apr;28(2):274-6.
PMID:3363109
Abstract
In experiments with hybrid mice (CBA X C57Bl)F1 and tetrahybrids (CBWA) a study was made of the radio-modifying properties of twelve quinoline derivatives. Among them three preparations, including quipazine [1(2-quinolyl)piperazine], possessed a 50% radioprotective effect. The radioprotective effect of piperazinylcinchonine acid hydrazides was the same as that of mexamine.
摘要
在对杂种小鼠（CBA×C57Bl）F1和四杂种（CBWA）进行的实验中，对12种喹啉衍生物的辐射修饰特性进行了研究。其中三种制剂，包括喹哌嗪[1-(2-喹啉基)哌嗪]，具有50%的辐射防护作用。哌嗪基辛可宁酸酰肼的辐射防护作用与美沙明相同。
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