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老年多发性骨髓瘤患者(年龄≥65 岁)自体干细胞移植:来自澳大利亚两个中心的经验。

Autologous stem cell transplantation in elderly multiple myeloma patients aged ≥65 years: a two-centre Australian experience.

机构信息

University Hospital Geelong, Barwon Health, Geelong, Victoria, Australia.

Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, Victoria, Australia.

出版信息

Intern Med J. 2021 Feb;51(2):280-283. doi: 10.1111/imj.15182.

Abstract

There are currently limited Australian data on the outcomes of autologous stem cell transplantation (ASCT) in elderly multiple myeloma (MM) patients. We present the largest cohort of elderly MM patients aged ≥65 years undergoing ASCT in Australia and report their outcomes based on our two-centre experience. Our study affirms that ASCT is well tolerated, safe and effective in elderly MM patients aged ≥65 years and should be considered an important component of treatment in patients who are fit enough for the procedure.

摘要

目前,澳大利亚关于老年多发性骨髓瘤(MM)患者自体干细胞移植(ASCT)结果的数据有限。我们报告了澳大利亚最大的老年 MM 患者队列(年龄≥65 岁)接受 ASCT 的结果,并根据我们的两中心经验报告了他们的结果。我们的研究证实,ASCT 在年龄≥65 岁的老年 MM 患者中是安全有效的,并且应该被认为是适合该手术的患者治疗的重要组成部分。

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