再矿化含氟生物活性玻璃复合材料。

Remineralising fluorine containing bioactive glass composites.

机构信息

Dental Physical Sciences, Dental Institute, Barts and the London Medical School, Queen Mary University of London, London E1 4NS, UK; University of Anbar, Colledge of Dentistry, Department of Paediatric, Orthodontic and Preventive Dentistry, Ramadi, Iraq.

Dental Physical Sciences, Dental Institute, Barts and the London Medical School, Queen Mary University of London, London E1 4NS, UK.

出版信息

Dent Mater. 2021 Apr;37(4):672-681. doi: 10.1016/j.dental.2021.01.004. Epub 2021 Feb 23.

DOI:10.1016/j.dental.2021.01.004

PMID:33632523

Abstract

OBJECTIVES

The objective was to investigate the mechanical properties, fluoride release and apatite formation of resin based dental composites based on a fluoride containing Bioactive Glass (BG) with and without a silylating agent.

METHODS

A SiO-PO-CaO-SrO-NaO-CaF BG was synthesized by the melt quench route. This glass and a commercially available inert glass (IG) were incorporated into a light cured BisGMA-TEGMA resin. The composite resins were then evaluated in terms of their ability to form apatite by Fourier Transform Infrared spectroscopy (FTIR) and by scanning electron microscopy (SEM) following immersion in artificial saliva at pH 4 (AS4) and pH 7 (AS7). The experiments were performed with and without silylation of the BG. The compressive strength and flexural strength were determined after 1, 28 and 84 days of immersion in the AS4 and AS7 immersion media.

RESULTS

The FTIR spectra of the BG composites exhibited split bands at approximately 560 and 600 cm corresponding to a apatite formation in the surface or on the surface under all immersion conditions. SEM showed the presence of a reacted layer of glass particles in the composite surface and the presence of a surface layer of apatite in AS7. The compressive strength and flexural strength were significantly higher for the silylated BG composites. The strengths of both silylated and non silylated BG composites and IG composites decreased upon immersion.

SIGNIFICANCE

BG composites exhibit reduced strengths upon immersion but still exhibit strengths comparable to existing composites after 84 days of immersion.

摘要

目的

本研究旨在探讨含氟生物活性玻璃（BG）的树脂基牙科复合材料的机械性能、氟释放和磷灰石形成，其中 BG 中添加了一种硅烷化剂。

方法

采用熔融淬火法合成了一种 SiO-PO-CaO-SrO-NaO-CaF 组成的 BG。将这种玻璃和一种市售惰性玻璃（IG）掺入光固化双酚 A 二缩水甘油醚甲基丙烯酸酯（BisGMA-TEGMA）树脂中。然后，通过傅里叶变换红外光谱（FTIR）和扫描电子显微镜（SEM）评估复合材料在 pH 4（AS4）和 pH 7（AS7）人工唾液中的成磷灰石能力。实验分别在 BG 硅烷化前后进行。将复合材料在 AS4 和 AS7 浸泡介质中浸泡 1、28 和 84 天后，测定其抗压强度和弯曲强度。

结果

BG 复合材料的 FTIR 光谱在大约 560 和 600 cm 处出现分裂带，对应于所有浸泡条件下表面或表面下的磷灰石形成。SEM 显示复合材料表面存在反应性玻璃颗粒层，在 AS7 中存在磷灰石表面层。硅烷化 BG 复合材料的抗压强度和弯曲强度明显更高。硅烷化和非硅烷化 BG 复合材料以及 IG 复合材料的强度在浸泡后均降低。