Uzan S, Beaufils M, Uzan M, Donsimoni R, Mareck A, Salat-Baroux J, Sureau C
Clinique universitaire Guy Le Lorier, Paris.
Rev Fr Gynecol Obstet. 1988 Feb;83(2):111-8.
An increased maternal plasma volume (PV) is a characteristic phenomenon of normal pregnancy, which may be related to a physiological decrease of peripheral resistances. The authors have studied the plasma volume of 1,105 patients distributed as follows: normal (387), permanently hypertensive patients (84), hypertensive patients during pregnancy (390), patients with apparently isolated RCIU (154) or with a pathological past-history during previous pregnancies (90). It appears that the PV is a sign of a severe HBP, and presents a rather early and good predictive value regarding the weight of the fetus and some complications such as severe UCIU and fetal death in utero. In case of pathological past events or pre-existing hypertension, the PV enables to differentiate rather well patients who will be prone to a complicated pregnancy. In view of these results, utilization and interpretation criteria of this parameter during pregnancies with hypertension or pregnancies in which there is a suspicion or a risk of intra-uterine growth delay, are defined.
孕妇血浆量（PV）增加是正常妊娠的一个特征性现象，这可能与外周阻力的生理性降低有关。作者研究了1105例患者的血浆量，分布如下：正常（387例）、持续性高血压患者（84例）、孕期高血压患者（390例）、明显孤立性胎儿宫内生长受限（RCIU）患者（154例）或既往妊娠有病理病史患者（90例）。看来，血浆量是重度高血压的一个标志，对于胎儿体重以及一些并发症，如重度胎儿宫内生长受限（UCIU）和胎儿宫内死亡，具有相当早且良好的预测价值。在有病理既往史或既往存在高血压的情况下，血浆量能够较好地区分哪些患者容易发生复杂妊娠。鉴于这些结果，定义了高血压妊娠或怀疑有或有宫内生长迟缓风险妊娠期间该参数的应用和解读标准。
