哥伦比亚儿童社区获得性尿路感染产超广谱 b-内酰胺酶肠杆菌科。

Extended-Spectrum b-Lactamase-Producing Enterobacteriaceae Causing Community-Acquired Urinary Tract Infections in Children in Colombia.

机构信息

Department of Pediatrics, Fundación Universitaria de Ciencias de la Salud (FUCS) - Hospital de San José and Hospital Infantil Universitario de San José de Bogotá, Colombia. Correspondence to: DrJhon Camacho, Associate Instructor, Department of Pediatrics FUCS,Calle 10, No.18-75 Bogota, Colombia.

Department of Pediatrics, Fundación Universitaria de Ciencias de la Salud (FUCS) - Hospital de San José and Hospital Infantil Universitario de San José de Bogotá, Colombia.

出版信息

Indian Pediatr. 2021 Feb 15;58(2):144-148.

PMID:33632945

Abstract

OBJECTIVE

To characterize the pediatric patients presenting at the two pediatric centers in Bogotá, with first isolate urine culture of community-acquired extended-spectrum b-lactamase (ESBL)-producing enterobacteriaceae.

METHODS

Review of microbiological data of children between January, 2012 and December, 2018, obtained using the WHONET software.

RESULTS

A total of 2657 Escherichia coli, Klebsiella spp and Proteus mirabilis - positive urine cultures were obtained within a 6-year period; data of 132 patients were finally selected. Frequency of ESBL-producing bacteria infections in community-acquired urinary tract infections (UTI) was 5%: 123 E. coli (93.2%), 7 K. pneumoniae (5.2%), 1 K. oxytoca (0.8%), and 1 P. mirabilis (0.8%).

CONCLUSION

A predominance of female sex, preschool children, and lower tract urinary infections were found, as well as a low frequency of comorbidities. Adequate sensitivity to amikacin and nitrofurantoin was found in this study.

摘要

目的

对在波哥大的两家儿科中心就诊的、首次分离出社区获得性产extended-spectrum b-lactamase（ESBL）肠杆菌科的小儿患者进行特征描述。

方法

使用 WHONET 软件回顾 2012 年 1 月至 2018 年 12 月期间获得的儿童微生物学数据。

结果

在 6 年期间共获得 2657 例大肠埃希菌、克雷伯菌属和奇异变形杆菌阳性尿液培养物；最终选择了 132 名患者的数据。社区获得性尿路感染（UTI）中 ESBL 产生菌感染的频率为 5%：123 株大肠埃希菌（93.2%）、7 株肺炎克雷伯菌（5.2%）、1 株产酸克雷伯菌（0.8%）和 1 株奇异变形杆菌（0.8%）。