群体特异性成分与HIV感染及进展至艾滋病的易感性
Group specific component and susceptibility to HIV infection and progression to AIDS.
作者信息
Putkonen P, Albert J, Karlsson A, Persson P O, Karlén K, Hjalmarsson K, Norberg R
机构信息
Department of Immunology, National Bacteriological Laboratory, Stockholm, Sweden.
出版信息
Scand J Infect Dis. 1988;20(1):11-4. doi: 10.3109/00365548809117211.
The distribution of phenotypes of the group specific component (Gc) was examined in 85 AIDS patients and in 40 couples, each consisting of one HIV seropositive patient and one seronegative sexual partner. Phenotype and allele frequencies in these groups did not differ significantly from those in a Swedish control population. Our observations did not indicate any involvement of the Gc system in susceptibility to HIV infection or progression to AIDS.
在85名艾滋病患者以及40对伴侣（每对伴侣由一名HIV血清阳性患者和一名血清阴性的性伴侣组成）中检测了群体特异性成分（Gc）的表型分布。这些群体中的表型和等位基因频率与瑞典对照人群中的表型和等位基因频率没有显著差异。我们的观察结果并未表明Gc系统参与了对HIV感染的易感性或发展为艾滋病的过程。
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