Department of Cardiac Pacing and Electrophysiology, IHU Liryc, Electrophysiology and Heart Modeling Institute, Univ. Bordeaux, Bordeaux University Hospital (CHU), Pessac-Bordeaux, France.
J Cardiovasc Electrophysiol. 2021 Apr;32(4):1182-1186. doi: 10.1111/jce.14974. Epub 2021 Mar 10.
Recent data of electrophysiological mapping in patients with Brugada syndrome (BrS) suggest that the presence of an abnormal arrhythmogenic substrate in the epicardial right ventricular outflow tract is responsible for ST-segment elevation and ventricular fibrillation (VF). Complete elimination of the epicardial abnormal potentials normalizes Brugada-pattern electrocardiogram and suppresses VF recurrence. We herein report the first case of BrS in which an injection of adenosine unmasked dormant conduction in the epicardial RVOT after the disappearance of the epicardial potentials.
最近 Brugada 综合征（BrS）患者的电生理标测数据表明，心外膜右心室流出道异常的致心律失常基质是导致 ST 段抬高和室颤（VF）的原因。完全消除心外膜异常电位可使 Brugada 样心电图正常化，并抑制 VF 复发。本文报告首例 BrS 病例，在心外膜电位消失后，腺苷注射揭示了心外膜 RVOT 中的休眠传导。
