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[使用抗高血压药物长期治疗的逐步方案控制动脉高血压的可能性。预防动脉高血压新药研究工作组]

[Possibilities of the control of arterial hypertension using the step-by-step schedule of long-term treatment with antihypertensive drugs. The Working Group on the Study of New Drugs for the Prevention of Arterial Hypertension].

出版信息

Ter Arkh. 1988;60(1):118-23.

PMID:3363497
Abstract

The results of therapy of 186 patients with stable arterial hypertension were described. Intervals in therapy for 3 mos and more were recorded in 5.9% of the patients. Monotherapy with one randomly chosen drug turned out possible for one year in 40.9% of the patients. In a group analysis a total antihypertensive effect (complete or partial) was noted in 93.5% of the patients. An individual analysis showed that a stable antihypertensive effect (over 6 mos running for one year) was achieved in 17.7%. A stable and prolonged intermittent effect (for 6 mos during one year with and without interruptions) was achieved in 46.2%. Regular control with relation to AH initial type was recommended: in 3 mos for a mild type, in 1.5 mos for a moderate type, in 0.5 mos in a severe type.

摘要

描述了186例稳定型动脉高血压患者的治疗结果。5.9%的患者记录到治疗间隔为3个月及更长时间。40.9%的患者使用一种随机选择的药物进行单药治疗可达一年。在组分析中,93.5%的患者有总体降压效果(完全或部分)。个体分析显示,17.7%的患者实现了稳定的降压效果(持续超过6个月达一年)。46.2%的患者实现了稳定且延长的间歇效果(一年中6个月有或无中断)。建议根据高血压初始类型进行定期监测:轻度类型每3个月监测一次,中度类型每1.5个月监测一次,重度类型每0.5个月监测一次。

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