Krivoshapkin V G, Pavlova N E
Ter Arkh. 1988;60(1):86-8.
Altogether 107 patients with chronic enterocolitis were examined. They were divided into 3 groups with relation to their attitude to alcohol: the 1st group-alcoholics, the 2nd risk group-hard drinking, the 3rd group-non-alcoholics. Severe disorders of the intestinal enzymatic activity (suppression of the intraduodenal amylolytic and proteolytic and intraluminal lactase activity) were revealed, the character of parietal digestion was changed. Atrophic duodenal changes among these patients were noted twice as more frequently as among the patients who did not consume alcohol or consumed it moderately. Expeditions revealed positive correlation between the morbidity and the type of living conditions in one or another climatic geographic area in the Jakut Republic.
共对107例慢性小肠结肠炎患者进行了检查。根据他们对酒精的态度,将其分为3组:第1组为酗酒者,第2组为高风险组(大量饮酒者),第3组为非酗酒者。结果发现肠道酶活性出现严重紊乱(十二指肠内淀粉酶、蛋白酶活性及肠腔内乳糖酶活性受到抑制),壁内消化特征发生改变。这些患者十二指肠萎缩性改变的发生率是不饮酒或适度饮酒患者的两倍。研究发现,雅库特共和国某一气候地理区域的发病率与生活条件类型之间存在正相关。