Department of Anesthesiology, First Affiliated Hospital of Nanchang University.
Department of Cardiology, The Second Affiliated Hospital of Nanchang University
Heart Surg Forum. 2021 Jan 20;24(1):E060-E064. doi: 10.1532/hsf.3331.
Acupoint catgut embedding (ACE) has been used safely for thousands of years in traditional Chinese medicine. The aim of this study was to assess whether ACE can improve insulin resistance and promote rapid recovery after open cardiac surgery.
A group of 200 patients undergoing cardiac surgery were randomly allocated to receive either ACE (ACE group) or sham ACE (SHAM group). The primary outcome of our trial was insulin resistance assessed 1, 3, 5, and 7 days after surgery. The homeostasis model assessment (HOMA-IR) was used to measure perioperative insulin resistance. Secondary outcomes included insulin, glucose, and inflammatory cytokine (interleukin (IL) 6 and IL-8) levels; time to extubation; incidence of infection; time to first feces; acute kidney injury; incidence of postoperative nausea and vomiting (PONV); length of stay in the ICU; length of hospital stay; and other clinical parameters.
The ACE group had lower insulin, glucose, IL-6, IL-8, and HOMA-IR levels than the SHAM group one week after the operation. The incidence of infection, incidence of PONV, time to drain removal, and length of hospital stay significantly were lower in the ACE group than in the SHAM group.
ACE can improve insulin resistance and promote rapid recovery after open cardiac surgery.
穴位埋线（ACE）在中医中已安全使用了数千年。本研究旨在评估 ACE 是否可以改善胰岛素抵抗并促进心脏直视手术后的快速康复。
将 200 名接受心脏手术的患者随机分为接受 ACE（ACE 组）或假 ACE（SHAM 组）治疗。本试验的主要结局是术后 1、3、5 和 7 天评估胰岛素抵抗。稳态模型评估（HOMA-IR）用于测量围手术期胰岛素抵抗。次要结局包括胰岛素、葡萄糖和炎症细胞因子（白细胞介素 (IL) 6 和 IL-8）水平；拔管时间；感染发生率；首次排便时间；急性肾损伤；术后恶心和呕吐（PONV）发生率；ICU 住院时间；住院时间；和其他临床参数。
与 SHAM 组相比，ACE 组术后一周胰岛素、葡萄糖、IL-6、IL-8 和 HOMA-IR 水平较低。ACE 组感染发生率、PONV 发生率、引流管拔除时间和住院时间明显低于 SHAM 组。
ACE 可改善胰岛素抵抗并促进心脏直视手术后的快速康复。
