Vermes I, Strik F
Department of Clinical Chemistry, H.d.K. Hospital, Oldenzaal, The Netherlands.
Stroke. 1988 May;19(5):631-3. doi: 10.1161/01.str.19.5.631.
Erythrocyte and leukocyte suspensions were prepared from 28 patients with chronic cerebrovascular disease and 30 age- and concomitant disease-matched control subjects. Cell filterability was studied with the new St. George's filtrometer, which can discriminate between initial filtration rate as an erythrocyte parameter and filter clogging as a leukocyte parameter. Compared with control subjects, a significant increase of filter clogging was found in the patients, suggesting decreased deformability or increased adhesiveness of leukocytes or both in chronic cerebrovascular disease.
从28例慢性脑血管疾病患者以及30例年龄和伴发疾病相匹配的对照受试者中制备红细胞和白细胞悬液。使用新型圣乔治滤过仪研究细胞过滤性，该滤过仪能够区分作为红细胞参数的初始过滤速率和作为白细胞参数的滤器堵塞情况。与对照受试者相比，发现患者的滤器堵塞显著增加，这表明慢性脑血管疾病患者白细胞的变形性降低或黏附性增加，或两者兼而有之。
