生前与死后 CT 检查腹水衰减的纵向比较。
Longitudinal comparison of ascites attenuation between antemortem and postmortem computed tomography.
机构信息
Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Department of Radiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
出版信息
Forensic Sci Int. 2021 Apr;321:110727. doi: 10.1016/j.forsciint.2021.110727. Epub 2021 Feb 18.
OBJECTIVE
To investigate the changes in ascites attenuation between antemortem (AMCT) and postmortem computed tomography (PMCT) analyses of the same subjects.
METHODS
Thirty-five subjects who underwent unenhanced or enhanced AMCT within 7 days before death, unenhanced PMCT, and autopsy were evaluated. In each subject, ascites attenuation was measured at similar sites on AMCT and PMCT. Attenuation changes were evaluated in 42 unenhanced AMCT/PMCT site pairs (23 subjects) and 20 enhanced AMCT/PMCT site pairs (12 subjects). Factors contributing to CT attenuation changes were also assessed, including the time interval between AMCT and PMCT, serum albumin level, estimated glomerular filtration rate, and ascites volume.
RESULTS
Significantly elevated CT attenuation was observed between enhanced AMCT and PMCT (12.2 ± 6.3 vs. 18.7 ± 10.4 Hounsfield units; paired t-test, p = 0.006), but not between unenhanced AMCT and PMCT (13.5 ± 8.9 vs. 13.4 ± 9.3; p = 0.554). A significant inverse association was observed between the degree of CT attenuation change and the time interval between enhanced AMCT and PMCT (Spearman's rank correlation coefficient, r = -0.56, p = 0.01).
CONCLUSIONS
We confirmed an elevated level of ascites attenuation on PMCT relative to AMCT in subjects who underwent enhanced AMCT shortly before death.
目的
研究同一患者的生前（AMCT）和死后（PMCT）计算机断层扫描（CT）分析中腹水衰减的变化。
方法
评估了 35 名在死亡前 7 天内接受过未增强或增强 AMCT、未增强 PMCT 和尸检的患者。在每个患者中，在 AMCT 和 PMCT 上的相似部位测量腹水衰减。在 42 对未增强 AMCT/PMCT 部位（23 例）和 20 对增强 AMCT/PMCT 部位（12 例）中评估衰减变化。还评估了导致 CT 衰减变化的因素，包括 AMCT 和 PMCT 之间的时间间隔、血清白蛋白水平、估计肾小球滤过率和腹水体积。
结果
在增强 AMCT 和 PMCT 之间观察到明显升高的 CT 衰减（12.2 ± 6.3 与 18.7 ± 10.4 亨氏单位；配对 t 检验，p = 0.006），但在未增强 AMCT 和 PMCT 之间没有（13.5 ± 8.9 与 13.4 ± 9.3；p = 0.554）。增强 AMCT 和 PMCT 之间 CT 衰减变化程度与时间间隔之间存在显著负相关（Spearman 秩相关系数，r = -0.56，p = 0.01）。
结论
我们证实了在死亡前不久接受增强 AMCT 的患者中，PMCT 相对于 AMCT 腹水衰减水平升高。
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