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[急性缺血性卒中与肌钙蛋白升高:诊断检查及治疗后果]

[Acute ischemic stroke and elevated troponin: Diagnostic work-up and therapeutic consequences].

作者信息

Grassl Niklas, Baumann Stefan, Kruska Mathieu, Fatar Marc, Akin Ibrahim, Platten Michael, Borggrefe Martin, Alonso Angelika, Szabo Kristina, Fastner Christian

机构信息

Neurologische Klinik, Universitätsmedizin Mannheim (UMM), Medizinische Fakultät Mannheim, Ruprecht-Karls-Universität Heidelberg, Mannheim Center for Translational Neuroscience (MCTN) und European Center for AngioScience (ECAS), Mannheim, Deutschland.

I. Medizinische Klinik, Universitätsmedizin Mannheim (UMM), Medizinische Fakultät Mannheim, Ruprecht-Karls-Universität Heidelberg, European Center for AngioScience (ECAS) und Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK) Standort Heidelberg/Mannheim, Mannheim, Deutschland.

出版信息

Dtsch Med Wochenschr. 2021 Apr;146(8):534-541. doi: 10.1055/a-1308-7490. Epub 2021 Feb 26.

DOI:10.1055/a-1308-7490
PMID:33636737
Abstract

Elevated troponin values are frequently detected in patients with acute ischemic stroke, requiring adequate diagnostic work-up due to the high cardiac mortality after stroke. Since dual platelet inhibition can cause secondary intracerebral hemorrhage careful consideration of invasive coronary intervention is mandatory. Based on three case reports, this review article presents a diagnostic algorithm taking into account latest findings from the literature.

摘要

急性缺血性卒中患者常检测到肌钙蛋白值升高,由于卒中后心脏死亡率高,需要进行充分的诊断检查。由于双重血小板抑制可导致继发性脑出血,因此必须谨慎考虑侵入性冠状动脉介入治疗。基于三例病例报告,本文献综述提出了一种考虑到文献最新发现的诊断算法。

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引用本文的文献

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Myocardial injury in spontaneous intracerebral hemorrhage is not predicted by prior cardiac disease or neurological status: results from the Mannheim Stroke database.自发性脑出血中的心肌损伤无法通过既往心脏病史或神经学状态预测:来自曼海姆卒中数据库的结果
Front Neurol. 2025 Feb 18;16:1510361. doi: 10.3389/fneur.2025.1510361. eCollection 2025.
2
[Acute ischemic stroke and troponin elevation: update of the Mannheim clinical algorithm].[急性缺血性卒中与肌钙蛋白升高:曼海姆临床算法的更新]
Inn Med (Heidelb). 2024 Aug;65(8):830-839. doi: 10.1007/s00108-024-01719-x. Epub 2024 Jun 3.
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Clinical predictors of prognosis in stroke patients after endovascular therapy.
血管内治疗后脑卒中患者预后的临床预测因素。
Sci Rep. 2024 Jan 5;14(1):667. doi: 10.1038/s41598-024-51356-5.
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Changes of Electrocardiogram and Myocardial Enzymes in Patients with Intracerebral Hemorrhage.脑出血患者的心电图和心肌酶变化。
Dis Markers. 2022 Feb 1;2022:9309444. doi: 10.1155/2022/9309444. eCollection 2022.
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Coronary Artery Disease in Patients Presenting With Acute Ischemic Stroke or Transient Ischemic Attack and Elevated Troponin Levels.急性缺血性卒中或短暂性脑缺血发作且肌钙蛋白水平升高患者的冠状动脉疾病
Front Neurol. 2022 Jan 13;12:781553. doi: 10.3389/fneur.2021.781553. eCollection 2021.