Williams J C
Department of Veterinary Science, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge 70803.
Vet Parasitol. 1988 Feb;27(1-2):85-7. doi: 10.1016/0304-4017(88)90064-7.
In order to determine the usefulness of the goat as a model host for Ostertagia ostertagi, a series of experiments was conducted in which young goats and calves were experimentally infected with L3 of calf-source and goat-source isolates. The goat-source isolate was derived from a continuous passage of the bovine parasite in goats. Patent infections resulted in 73 out of 86 inoculated goats (85%). The largest number of patent infections was observed when inoculation consisted of a single dose of goat-source larvae. Percentage establishment of infection was generally low in goats inoculated with either larval source. Time taken to achieve patency in goats was frequently within the range normal for cattle infections, but was often extended (21-67 days). With the exception of the generally higher level of establishment of goat- or calf-source isolates in calves and the low frequency of the vulval flap in adult female worms established in goats, little difference was observed in percentage establishment or worm population characteristics of the two isolates in goats.
为了确定山羊作为牛奥斯特他线虫的模型宿主的实用性，进行了一系列实验，其中用犊牛源和山羊源分离株的L3对幼龄山羊和犊牛进行了实验性感染。山羊源分离株源自牛寄生虫在山羊中的连续传代。86只接种山羊中有73只（85%）出现显性感染。当接种由单剂量山羊源幼虫组成时，观察到的显性感染数量最多。用两种幼虫源接种的山羊的感染定植率通常较低。山羊达到显性感染所需的时间通常在牛感染的正常范围内，但往往会延长（21 - 67天）。除了犊牛中山羊源或犊牛源分离株的定植水平普遍较高以及山羊中成年雌虫的外阴瓣出现频率较低外，在山羊中两种分离株的定植率或虫体种群特征几乎没有差异。
