Collége Français d'Echographie Foetale, CFEF, 34820, Teyran, France.
Assistance Publique-Hôpitaux de Paris, Hôpital Trousseau, Sorbonne Université, Paris, France.
BMC Pregnancy Childbirth. 2021 Feb 27;21(1):167. doi: 10.1186/s12884-021-03640-9.
The impact of using the Intergrowth (IG) dating formulae in comparison to the commonly used Robinson dating on the evaluation of biometrics and estimated fetal weight (EFW) has not been evaluated.
Nationwide cross-sectional study of routine fetal ultrasound biometry in low-risk pregnant women whose gestational age (GA) had been previously assessed by a first trimester CRL measurement. We compared the CRL-based GA according to the Robinson formula and the IG formula. We evaluated the fetal biometric measurements as well as the EFW taken later in pregnancy depending on the dating formula used. Mean and standard deviation of the Z scores as well as the number and percentage of cases classified as <3rd, < 10th, >90th and > 97th percentile were compared.
Three thousand five hundred twenty-two low-risk women with scans carried out after 18 weeks were included. There were differences of zero, one and 2 days in 642 (18.2%), 2700 (76.7%) and 180 (5%) when GA was estimated based on the Robinson or the IG formula, respectively. The biometry Z scores assessed later in pregnancy were all statistically significantly lower when the Intergrowth-based dating formula was used (p < 10). Likewise, the number and percentage of foetuses classified as <3rd, < 10th, >90th and > 97th percentile demonstrated significant differences. As an example, the proportion of SGA foetuses varied from 3.46 to 4.57% (p = 0.02) and that of LGA foetuses from 17.86 to 13.4% (p < 10).
The dating formula used has a quite significant impact on the subsequent evaluation of biometry and EFW. We suggest that the combined and homogeneous use of a recent dating standard, together with prescriptive growth standards established on the same low-risk pregnancies, allows an optimal assessment of fetal growth.
与常用的 Robinson 日期相比，使用 Intergrowth（IG）日期公式对生物测量和估计胎儿体重（EFW）的评估的影响尚未得到评估。
对低危孕妇进行常规胎儿超声生物测量的全国性横断面研究，这些孕妇的孕龄（GA）之前已通过第一 trimester CRL 测量进行评估。我们比较了根据 Robinson 公式和 IG 公式计算的基于 CRL 的 GA。我们根据使用的约会公式评估了胎儿生物测量值以及妊娠后期的 EFW。比较了 Z 分数的平均值和标准差，以及被分类为 <3 分、<10 分、>90 分和 >97 分的病例数和百分比。
共纳入 3522 名在 18 周后进行扫描的低危妇女。分别基于 Robinson 或 IG 公式估计 GA 时，642（18.2%）、2700（76.7%）和 180（5%）的 GA 存在零、一和两天的差异。妊娠后期评估的生物测量 Z 评分均显著降低（p<10）当使用基于 Intergrowth 的约会公式时。同样，被分类为 <3 分、<10 分、>90 分和 >97 分的胎儿数量和百分比也有显著差异。例如，SGA 胎儿的比例从 3.46%到 4.57%（p=0.02），LGA 胎儿的比例从 17.86%到 13.4%（p<10）。
使用的约会公式对随后的生物测量和 EFW 评估有相当大的影响。我们建议，使用最近的约会标准并结合在同一低危妊娠中建立的规定生长标准，可以对胎儿生长进行最佳评估。
