UK Small Area Health Statistics Unit, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.
Imperial College Healthcare NHS Trust, London, UK.
Arch Dis Child Fetal Neonatal Ed. 2018 May;103(3):F264-F270. doi: 10.1136/archdischild-2016-311790. Epub 2017 Aug 5.
Birth weight is a strong predictor of infant mortality, morbidity and later disease risk. Previous work from the 1980s indicated a shift in the UK towards heavier births; this descriptive analysis looks at more recent trends.
Office for National Statistics (ONS) registration data on 17.2 million live, single births from 1986 to 2012 were investigated for temporal trends in mean birth weight, potential years of birth weight change and changes in the proportions of very low (<1500 g), low (<2500 g) and high (≥4000 g) birth weight. Analysis used multiple linear and logistic regression adjusted for maternal age, marital status, area-level deprivation and ethnicity. Additional analyses used the ONS NHS Numbers for Babies data set for 2006-2012, which has information on individual ethnicity and gestational age.
Over 27 years there was an increase in birth weight of 43 g (95% CI 42 to 44) in females and 44 g (95% CI 43 to 45) in males, driven by birth weight increases between 1986-1990 and 2007-2012. There was a concurrent decreased risk of having low birth weight but an 8% increased risk in males and 10% increased risk in females of having high birth weight. For 2006-2012 the birth weight increase was greater in preterm as compared with term births.
Since 1986 the birth weight distribution of live, single births in England and Wales has shifted towards heavier births, partly explained by increases in maternal age and non-white ethnicity, as well as changes in deprivation levels. Other potential influences include increases in maternal obesity and reductions in smoking prevalence particularly following the introduction of legislation restricting smoking in public places in 2007.
出生体重是婴儿死亡率、发病率和后期疾病风险的强有力预测指标。20 世纪 80 年代的先前研究表明,英国的出生体重呈上升趋势;本描述性分析着眼于更近的趋势。
研究了 1986 年至 2012 年间 1720 万例活产、单胎出生的英国国家统计局(ONS)登记数据,以调查出生体重的平均水平、潜在出生体重变化年数以及极低体重(<1500g)、低体重(<2500g)和高体重(≥4000g)出生体重比例的变化趋势。分析使用了经产妇年龄、婚姻状况、地区贫困程度和种族调整后的多元线性和逻辑回归。其他分析使用了 2006-2012 年的英国国家统计局国民保健制度婴儿数据,其中包含了个体种族和胎龄信息。
在 27 年期间,女性出生体重增加了 43g(95%CI 42 至 44),男性增加了 44g(95%CI 43 至 45),这主要是由于 1986-1990 年和 2007-2012 年之间的出生体重增加。低出生体重的风险降低,但男性高出生体重的风险增加了 8%,女性增加了 10%。对于 2006-2012 年,早产出生体重的增加大于足月出生体重。
自 1986 年以来,英格兰和威尔士活产、单胎出生的体重分布已向较重的出生体重转移,这部分归因于产妇年龄和非白种人种族的增加,以及贫困程度的变化。其他潜在影响因素包括母亲肥胖的增加和吸烟率的降低,尤其是在 2007 年出台限制公共场所吸烟的立法之后。