Rangnekar Ranjit D, Vilanilam George C, Krishnakumar K, Abraham Mathew
Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Neurol India. 2021 Jan-Feb;69(1):153-156. doi: 10.4103/0028-3886.310114.
The aim of this case series is to report two cases of giant cavernomas treated at a tertiary level centre along with a literature review on the differences between giant cavernomas and normal sized cavernomas.
The first case was that of a 13-year-old male with habitual seizures since one year of age with normal examination findings. His imaging revealed a large parieto-occipital lesion which was excised microsurgically after a parieto-occipital craniotomy and a transcortical approach. The second case was a 26-year-old male who presented with generalised seizures and bilateral visual loss. Imaging was suggestive of a large left lateral ventricular lesion. A left fronto-temporo-parietal craniotomy was done followed by transventricular microsurgical excision. Histopathology of both cases were reported to be cavernomas. The first patient had transient hemiparesis post-operatively which improved within 24 hours. Eventually, both patients had an uneventful follow-up.
Microsurgical excision remains the treatment of choice for giant cavernomas. In toto excision may be advocated depending upon the location of the cavernoma especially with respect to eloquence and venous anatomy.
本病例系列的目的是报告在三级中心治疗的两例巨大海绵状血管瘤病例,并对巨大海绵状血管瘤与正常大小海绵状血管瘤之间的差异进行文献综述。
第一例是一名13岁男性,自1岁起就有习惯性癫痫发作,检查结果正常。他的影像学检查显示一个巨大的顶枕部病变,在进行顶枕部开颅手术和经皮质入路后,通过显微手术切除。第二例是一名26岁男性,表现为全身性癫痫发作和双侧视力丧失。影像学检查提示左侧侧脑室有一个巨大病变。进行了左额颞顶开颅手术,随后经脑室进行显微手术切除。两例病例的组织病理学报告均为海绵状血管瘤。第一例患者术后出现短暂性偏瘫,在24小时内有所改善。最终,两名患者的随访情况均良好。
显微手术切除仍然是巨大海绵状血管瘤的首选治疗方法。根据海绵状血管瘤的位置,特别是与脑功能区和静脉解剖结构的关系,可能主张进行全切。