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严重低钠血症伴急性肾损伤患者行间歇性血液透析前用 3%生理盐水推注成功纠正血钠水平。

Successful Sodium Level Correction with a 3% Saline Bolus before Intermittent Hemodialysis for a Patient with Severe Hyponatremia Accompanied by Acute Kidney Injury.

机构信息

Department of Nephrology, National Hospital Organization Kyoto Medical Center, Japan.

出版信息

Intern Med. 2021 Aug 15;60(16):2645-2649. doi: 10.2169/internalmedicine.6667-20. Epub 2021 Mar 1.

Abstract

A 60-year-old man presented to the emergency department with lightheadedness. He had severe hyponatremia (109 mEq/L) complicated by acute kidney injury (AKI) (serum creatinine: 9.08 mg/dL). Because he was somnolescent, his hyponatremia was initially treated by administering a 130-mL bolus of 3% saline 2 to 5 times per day for 5 days. He subsequently underwent intermittent hemodialysis without any neurological problems. Previous reports have described patients with hyponatremia and AKI being treated with continuous renal replacement therapy. However, our strategy might be a feasible, low-cost treatment strategy of treating patients with hyponatremia and AKI who do not require immediate hemodialysis.

摘要

一位 60 岁男性因头晕到急诊科就诊。他患有严重的低钠血症(109mEq/L),并伴有急性肾损伤(AKI)(血肌酐:9.08mg/dL)。由于他嗜睡,他的低钠血症最初通过每天 2 至 5 次给予 130 毫升 3%盐水的推注来治疗,共治疗 5 天。随后他进行了间歇性血液透析,没有出现任何神经问题。先前的报告描述了患有低钠血症和 AKI 的患者接受连续肾脏替代治疗。然而,我们的策略可能是一种可行的、低成本的治疗策略,适用于那些不需要立即进行血液透析的低钠血症和 AKI 患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc3e/8429311/4189c6580d3f/1349-7235-60-2645-g001.jpg

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