Gastroenterological Center, Yokohama City University Medical Center, Japan.
Division of Gastroenterology, Yokohama City University Graduate School of Medicine, Japan.
Intern Med. 2021 Aug 15;60(16):2607-2612. doi: 10.2169/internalmedicine.6755-20. Epub 2021 Mar 1.
A 74-year-old woman with a cyst in her pancreatic tail was referred to our hospital. Computed tomography confirmed a large cystic lesion with irregular wall thickening, abdominal lymph node swelling, and ascites. We diagnosed her with an unresectable mucinous cystic neoplasm, since ascites cytology revealed adenocarcinoma. The patient received chemotherapy up to the fifth line for 55.2 months. Gemcitabine plus nab-paclitaxel and modified FOLFIRINOX achieved a partial response with a progression-free survival time of 12.1 and 20.4 months, respectively. The overall survival time from the beginning of first-line chemotherapy was 69.4 months.
一位 74 岁女性因胰腺尾部囊肿就诊于我院。计算机断层扫描（CT）证实存在一个大的囊性病变，伴有不规则的壁增厚、腹部淋巴结肿大和腹水。腹水细胞学检查显示腺癌，因此我们诊断为不可切除的黏液性囊腺瘤。患者接受了 55.2 个月的五线化疗。吉西他滨联合白蛋白紫杉醇和改良 FOLFIRINOX 方案治疗的部分缓解率分别为 12.1%和 20.4%，无进展生存期分别为 12.1 个月和 20.4 个月。从一线化疗开始的总生存期为 69.4 个月。
