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一名三个月大男婴的小儿炎症性肠病

Infantile Inflammatory Bowel Disease in a Three-Month-Old-Boy.

作者信息

Iida Chie, Tatsumi Ako, Fujino Hisanori, Anzai Kaori, Sumimoto Shinichi

机构信息

Pediatrics, Osaka Red Cross Hospital, Osaka, JPN.

出版信息

Cureus. 2021 Jan 16;13(1):e12743. doi: 10.7759/cureus.12743.

DOI:10.7759/cureus.12743
PMID:33643722
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7884542/
Abstract

Very early-onset inflammatory bowel disease (VEO-IBD) and infantile IBD occur in children aged less than six years and less than two years, respectively. Since childhood-onset IBD seems to be a more aggressive and rapidly progressive disease than adult-onset IBD, it should therefore be diagnosed and treated immediately. Here, we report a case of infantile IBD in a three-month-old infant with clinical and biochemical manifestations. The diagnosis was confirmed with histopathological evidence. The patient had been treated successfully with both mesalazine and prednisolone and with mesalazine alone on follow-up.

摘要

极早发型炎症性肠病(VEO-IBD)和婴儿型炎症性肠病分别发生在6岁以下和2岁以下的儿童中。由于儿童期发病的炎症性肠病似乎比成人期发病的炎症性肠病更具侵袭性且进展迅速,因此应立即进行诊断和治疗。在此,我们报告一例三个月大婴儿患婴儿型炎症性肠病的病例及其临床和生化表现。通过组织病理学证据确诊。该患者先后成功接受了美沙拉嗪和泼尼松龙联合治疗以及后续单独使用美沙拉嗪的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/296c15a10805/cureus-0013-00000012743-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/0ca53cef31fc/cureus-0013-00000012743-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/22f7fd5418f8/cureus-0013-00000012743-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/296c15a10805/cureus-0013-00000012743-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/0ca53cef31fc/cureus-0013-00000012743-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/22f7fd5418f8/cureus-0013-00000012743-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c66/7884542/296c15a10805/cureus-0013-00000012743-i03.jpg

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本文引用的文献

1
Current concepts in pediatric inflammatory bowel disease; IL10/IL10R colitis as a model disease.儿童炎症性肠病的当前概念;以IL10/IL10R结肠炎作为模型疾病
Int J Pediatr Adolesc Med. 2019 Mar;6(1):1-5. doi: 10.1016/j.ijpam.2019.02.002. Epub 2019 Mar 12.
2
The Impact of Inflammatory Bowel Disease in Canada 2018: Children and Adolescents with IBD.《2018年炎症性肠病在加拿大的影响:患有炎症性肠病的儿童和青少年》
J Can Assoc Gastroenterol. 2019 Feb;2(Suppl 1):S49-S67. doi: 10.1093/jcag/gwy056. Epub 2018 Nov 2.
3
Recent Advance in Very Early Onset Inflammatory Bowel Disease.
叙利亚 3 例婴儿炎症性肠病:病例系列。
J Med Case Rep. 2024 Mar 18;18(1):160. doi: 10.1186/s13256-024-04456-9.
极早发型炎症性肠病的最新进展
Pediatr Gastroenterol Hepatol Nutr. 2019 Jan;22(1):41-49. doi: 10.5223/pghn.2019.22.1.41. Epub 2019 Jan 10.
4
Inflammatory bowel diseases and primary immunodeficiency diseases.炎症性肠病和原发性免疫缺陷病。
Immunol Med. 2018 Dec;41(4):154-161. doi: 10.1080/25785826.2018.1556025. Epub 2019 Jan 11.
5
Clinical aspects and treatments for pediatric inflammatory bowel disease.儿童炎症性肠病的临床特征与治疗方法
Intest Res. 2019 Jan;17(1):17-23. doi: 10.5217/ir.2018.00139. Epub 2019 Jan 9.
6
Higher Morbidity of Monogenic Inflammatory Bowel Disease Compared to the Adolescent Onset Inflammatory Bowel Disease.与青少年起病的炎症性肠病相比,单基因炎症性肠病的发病率更高。
Pediatr Gastroenterol Hepatol Nutr. 2018 Jan;21(1):34-42. doi: 10.5223/pghn.2018.21.1.34. Epub 2018 Jan 12.
7
The role of monogenic disease in children with very early onset inflammatory bowel disease.单基因疾病在极早发型炎症性肠病患儿中的作用。
Curr Opin Pediatr. 2017 Oct;29(5):566-571. doi: 10.1097/MOP.0000000000000531.
8
Very-Early-Onset Inflammatory Bowel Disease.极早发型炎症性肠病
Gastroenterol Hepatol (N Y). 2015 Aug;11(8):554-6.
9
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.关联分析确定了38个炎症性肠病的易感基因座,并突出了不同人群间共有的遗传风险。
Nat Genet. 2015 Sep;47(9):979-986. doi: 10.1038/ng.3359. Epub 2015 Jul 20.
10
The diagnostic approach to monogenic very early onset inflammatory bowel disease.单基因极早发型炎症性肠病的诊断方法
Gastroenterology. 2014 Nov;147(5):990-1007.e3. doi: 10.1053/j.gastro.2014.07.023. Epub 2014 Jul 21.