Alshamam Mohsen S, Gurung Dawa O, Nso Nso, Saliaj Merjona, Seitaj Adja
Department of Medicine, Icahn School of Medicine at Mount Sinai, Queens Hospital Center, NYC, USA.
Internal Medicine, New York City (NYC) Health + Hospitals-Queens, NYC, USA.
Cureus. 2021 Jan 17;13(1):e12746. doi: 10.7759/cureus.12746.
Rhabdomyolysis has many causes; however, hypothyroidism is a rare cause of such a condition. Usually, management is similar in many cases, but some exceptions do exist, especially in the case of hypothyroidism. Thus, we reviewed the literature to investigate further precipitant factors, clinical presentations, complications, management, and prognoses. We report a 19-year-old male with a history of hypothyroidism who was brought in for questionable suicidal ideation. Although asymptomatic, he was found to have an acute kidney injury (AKI). Further investigations revealed significantly elevated levels of creatine kinase (CK) and thyroid-stimulating hormone (TSH) in the setting of medication non-compliance. Management with intravenous (IV) fluids and thyroid hormone replacement resulted in an improvement in AKI and CK levels.
横纹肌溶解症有多种病因；然而，甲状腺功能减退是导致这种病症的罕见原因。通常，许多情况下的治疗方法相似，但也存在一些例外情况，尤其是在甲状腺功能减退的病例中。因此，我们查阅了文献，以进一步研究诱发因素、临床表现、并发症、治疗方法及预后情况。我们报告了一名19岁男性，有甲状腺功能减退病史，因可疑的自杀意念前来就诊。尽管他没有症状，但被发现患有急性肾损伤（AKI）。进一步检查发现，在未遵医嘱服药的情况下，肌酸激酶（CK）和促甲状腺激素（TSH）水平显著升高。通过静脉输液和甲状腺激素替代治疗，急性肾损伤和肌酸激酶水平有所改善。
