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新生儿重症监护病房中的泛菌感染

Pantoea Infections in the Neonatal Intensive Care Unit.

作者信息

Mani Srinivasan, Nair Jayasree

机构信息

Pediatrics/Neonatology, State University of New York, Buffalo, USA.

出版信息

Cureus. 2021 Feb 3;13(2):e13103. doi: 10.7759/cureus.13103.

Abstract

is a plant pathogen infrequently reported to cause opportunistic bloodstream infections. This gram-negative bacillus is a rare cause of hospital-acquired infections in newborn infants with high mortality. Since the creation of the new genus in 1989, the evidence base available to neonatal health care providers is limited. Most of the available literature consists of case reports and case series. This review aims to consolidate the current reported literature on Pantoea infections, focusing on newborn infants and the neonatal intensive care unit (NICU). Prematurity and the associated relative immunocompromised state are major risk factors for hospital-acquired infections due to in newborn infants. Recent advances in molecular biology have improved our understanding of the cross-kingdom pathogenesis exhibited by . Respiratory symptoms and association with central venous lines are the most common clinical presentation of bacteremia in newborn infants. Early institution of appropriate antibiotic therapy against this organism could be lifesaving. Therefore, it is critical for neonatologists to understand the clinical spectrum of infections in NICUs.

摘要

是一种很少被报道会引起机会性血流感染的植物病原体。这种革兰氏阴性杆菌是新生儿医院获得性感染的罕见病因,死亡率很高。自1989年创建新属以来,新生儿医疗保健提供者可获得的证据基础有限。现有文献大多由病例报告和病例系列组成。本综述旨在整合目前已报道的关于泛菌感染的文献,重点关注新生儿和新生儿重症监护病房(NICU)。早产及相关的相对免疫功能低下状态是新生儿因泛菌导致医院获得性感染的主要危险因素。分子生物学的最新进展增进了我们对泛菌所表现出的跨界发病机制的理解。呼吸道症状以及与中心静脉导管的关联是新生儿泛菌血症最常见的临床表现。早期对这种病原体采取适当的抗生素治疗可能挽救生命。因此,新生儿科医生了解NICU中泛菌感染的临床谱至关重要。

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