Baeg N J, Bodenheimer H C, Burchard K
Department of Internal Medicine, Catholic Medical College, Seoul, Korea.
Am J Gastroenterol. 1988 May;83(5):569-71.
We report a case of fulminant hepatic necrosis occurring in the setting of acetaminophen overdose and chronic alcohol use. The pathology of severe acute toxicity is documented with a surgical biopsy. Follow-up liver biopsy 4 yr later documents hepatic regeneration without cirrhosis. Maintenance of the hepatic reticulin framework in the face of acute hepatic necrosis was well documented, and may be a useful prognostic feature indicating a potential for the maintenance of normal hepatic architecture following regeneration.
我们报告了一例在对乙酰氨基酚过量服用及长期饮酒情况下发生的暴发性肝坏死病例。通过手术活检记录了严重急性毒性的病理情况。4年后的随访肝活检显示肝脏再生且无肝硬化。面对急性肝坏死时肝网状纤维支架得以维持，这一点有充分记录，并且可能是一个有用的预后特征，表明再生后维持正常肝脏结构的可能性。
