Xu Dan-Feng, Wu Bing, Wang Jin-Xin, Yu Jian, Xie Jian-Xin
Department of Orthopedic Surgery, Shaoxing Central Hospital, Shaoxing 312000, Zhejiang Province, China.
World J Clin Cases. 2021 Feb 16;9(5):1096-1102. doi: 10.12998/wjcc.v9.i5.1096.
Guillain-Barré syndrome (GBS) is a rare disorder that typically presents with ascending weakness, pain, paraesthesias, and numbness, which mimic the findings in lumbar spinal stenosis. Here, we report a case of severe lumbar spinal stenosis combined with GBS.
A 70-year-old man with a history of lumbar spinal stenosis presented to our emergency department with severe lower back pain and lower extremity numbness. Magnetic resonance imaging confirmed the diagnosis of severe lumbar spinal stenosis. However, his symptoms did not improve postoperatively and he developed dysphagia and upper extremity numbness. An electromyogram was performed. Based on his symptoms, physical examination, and electromyogram, he was diagnosed with GBS. After 5 d of intravenous immunoglobulin (0.4 g/kg/d for 5 d) therapy, he gained 4/5 of strength in his upper and lower extremities and denied paraesthesias. He had regained 5/5 of strength in his extremities when he was discharged and had no symptoms during follow-up.
GBS should be considered in the differential diagnosis of spinal disorder, even though magnetic resonance imaging shows severe lumbar spinal stenosis. This case highlights the importance of a careful diagnosis when a patient has a history of a disease and comes to the hospital with the same or similar symptoms.
吉兰 - 巴雷综合征(GBS)是一种罕见疾病,通常表现为进行性肌无力、疼痛、感觉异常和麻木,这些症状与腰椎管狭窄的表现相似。在此,我们报告一例严重腰椎管狭窄合并GBS的病例。
一名有腰椎管狭窄病史的70岁男性因严重下背部疼痛和下肢麻木就诊于我院急诊科。磁共振成像确诊为严重腰椎管狭窄。然而,术后他的症状并未改善,且出现吞咽困难和上肢麻木。进行了肌电图检查。根据其症状、体格检查和肌电图,他被诊断为GBS。经过5天的静脉注射免疫球蛋白(0.4 g/kg/d,共5天)治疗后,他的上下肢肌力恢复到4/5,且无感觉异常。出院时他的四肢肌力已恢复到5/5,随访期间无任何症状。
即使磁共振成像显示严重腰椎管狭窄,在脊柱疾病的鉴别诊断中也应考虑GBS。该病例强调了患者有疾病史且因相同或相似症状就医时进行仔细诊断的重要性。