Irma L Rangel College of Pharmacy, Texas A&M University, College Station, TX.
J Manag Care Spec Pharm. 2021 Mar;27(3):392-398. doi: 10.18553/jmcp.2021.27.3.392.
Puerto Ricans are the Hispanic subgroup with the highest adjusted prevalence of statin-eligible patients. However, no study has described statin utilization and adherence among subjects living on the island of Puerto Rico. To (a) estimate the prevalence of beneficiaries with diabetes aged between 40 and 75 years; (b) estimate the prevalence of statin utilization among beneficiaries with diabetes; and (c) estimate secondary adherence to statins among beneficiaries with diabetes. With pharmacy claims data from a commercial pharmacy benefit manager (PBM) in the Commonwealth of Puerto Rico, this study used a retrospective longitudinal design to analyze all pharmacy claims generated by 115,674 beneficiaries aged between 40 and 75 years with continuous enrollment during 2018. Beneficiaries with diabetes were defined by having ≥ 2 pharmacy claims for antidiabetic agents during 2018. Statin utilization was defined by having ≥ 1 pharmacy claim for statins among beneficiaries with diabetes. The proportion of days covered (PDC) was used to measure secondary adherence to statins. Parametric and nonparametric statistics were used to describe statin utilization and adherence. The prevalence of beneficiaries with diabetes was 7.8%. Of the 8,975 beneficiaries with diabetes, 5,129 (57.1%) received ≥ 1 prescription for a statin. Older males with diabetes were more likely to receive prescriptions for statins. The median PDC for the 4,553 beneficiaries with ≥ 2 prescriptions for statins was 63.4%; 3,306 (72.6%) beneficiaries filled their statin prescriptions for a 30-day supply only; and 1,252 (27.5%) beneficiaries had a PDC ≥ 80%. The highest PDC (92.3%) was observed for beneficiaries who received statins for a 90-day supply only. This is the first study that has measured statin utilization and adherence among patients with diabetes living in Puerto Rico. The utilization and adherence to statins among privately insured beneficiaries with diabetes in Puerto Rico are suboptimal. Future studies should focus on understanding the reasons for the suboptimal use of statins and on potential interventions at the beneficiary and provider level to increase statin utilization. No outside funding supported this study. The authors have no conflicts of interest or financial disclosures to disclose related to this study.
波多黎各人是西班牙裔亚组中调整后最符合他汀类药物适用患者标准的人群。然而,尚无研究描述过居住在波多黎各岛上的人群中他汀类药物的使用情况和用药依从性。(a)估计年龄在 40 至 75 岁之间的糖尿病受益人的患病率;(b)估计糖尿病受益人中他汀类药物的使用情况;(c)估计糖尿病受益人的他汀类药物二级用药依从性。本研究利用波多黎各商业药房福利管理公司(PBM)的药房理赔数据,采用回顾性纵向设计,对 2018 年期间连续参保的 115674 名年龄在 40 至 75 岁之间的所有药房理赔进行了分析。糖尿病受益人的定义是在 2018 年期间有≥2 次用于治疗糖尿病的药物理赔。糖尿病受益人中的他汀类药物使用情况是指有≥1 次他汀类药物理赔。比例用药天数(PDC)用于衡量他汀类药物的二级用药依从性。采用参数和非参数统计方法描述他汀类药物的使用和用药依从性。糖尿病受益人的患病率为 7.8%。在 8975 名患有糖尿病的受益人中,有 5129 名(57.1%)接受了≥1 次他汀类药物处方。年龄较大的男性糖尿病患者更有可能接受他汀类药物的处方。在≥2 次开具他汀类药物处方的 4553 名受益人中,中位数 PDC 为 63.4%;3306 名(72.6%)受益人的他汀类药物处方仅为 30 天供应量;1252 名(27.5%)受益人的 PDC≥80%。仅接受 90 天供应量他汀类药物的受益人的 PDC 最高(92.3%)。这是第一项评估居住在波多黎各的糖尿病患者他汀类药物使用情况和用药依从性的研究。波多黎各私人保险糖尿病患者他汀类药物的使用和用药依从性并不理想。未来的研究应重点了解他汀类药物使用不理想的原因,并在受益人和提供者层面上考虑潜在的干预措施,以提高他汀类药物的使用。本研究无外部资金支持。作者与本研究无利益冲突或财务披露。