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特定活动与中老年人群认知能力下降轨迹:一项为期五年的纵向队列研究。

Specific Activities and the Trajectories of Cognitive Decline Among Middle-Aged and Older Adults: A Five-Year Longitudinal Cohort Study.

机构信息

Department of Sociology, Shenzhen University, Shenzhen, China.

Centre for Biomedical Information Technology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.

出版信息

J Alzheimers Dis. 2021;80(3):1039-1050. doi: 10.3233/JAD-201268.

Abstract

BACKGROUND

How specific activities influence cognitive decline among different age groups, especially the late middle-aged and the early old, remains inadequately studied.

OBJECTIVE

To examine the association between specific activities with trajectories of cognitive functions in different age groups in China.

METHODS

A longitudinal cohort study was conducted based on data from the China Health and Retirement Longitudinal Study (CHARLS). Mixed effects growth models were applied to analyze the association between specific activities and cognitive functions.

RESULTS

Interacting with friends (infrequent: β= 0.13, confidence interval [CI] = 0.03 to 0.22; daily: β= 0.19, CI = 0.09 to 0.28), playing Mah-jong or other games (infrequent: β= 0.12, CI = 0.02 to 0.22; daily:β= 0.26, CI = 0.10 to 0.42), infrequent providing help to others (β= 0.24, CI = 0.11 to 0.37), and going to a sport (infrequent: β= 0.31, CI = 0.08 to 0.54); daily: β= 0.22, CI = 0.05 to 0.38) are significantly associated with participants' memory. Infrequently playing Mah-jong or other games (β= 0.30, CI = 0.17 to 0.43) and daily sports (β= 0.24, CI = 0.03 to 0.45) are significantly associated with better mental status. Effect of each activity varies among population of different age, education level, gender, and residence.

CONCLUSION

This study identifies four social activities that are associated with better cognitive functions, and provides a comprehensive, in-depth understanding on the specific protective effect of each activity among different subgroups.

摘要

背景

特定活动如何影响不同年龄组的认知能力下降,尤其是中老年和老年早期,这方面的研究仍不够充分。

目的

探讨中国不同年龄组特定活动与认知功能轨迹之间的关系。

方法

本研究基于中国健康与养老追踪调查(CHARLS)数据进行了一项纵向队列研究。采用混合效应增长模型分析特定活动与认知功能之间的关系。

结果

与朋友互动(不频繁:β=0.13,置信区间 [CI]:0.03 至 0.22;每天:β=0.19,CI:0.09 至 0.28)、玩麻将或其他游戏(不频繁:β=0.12,CI:0.02 至 0.22;每天:β=0.26,CI:0.10 至 0.42)、不频繁提供帮助他人(β=0.24,CI:0.11 至 0.37)和参加体育运动(不频繁:β=0.31,CI:0.08 至 0.54;每天:β=0.22,CI:0.05 至 0.38)与参与者的记忆显著相关。不频繁地玩麻将或其他游戏(β=0.30,CI:0.17 至 0.43)和每天参加运动(β=0.24,CI:0.03 至 0.45)与更好的心理状态显著相关。每种活动的效果因年龄、教育程度、性别和居住地不同的人群而异。

结论

本研究确定了四项与认知功能更好相关的社会活动,并深入了解了每个活动在不同亚组中的具体保护作用。

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