龋齿与儿科患者贫血相关：系统文献回顾。

Dental Caries Are Associated with Anemia in Pediatric Patients: A Systematic Literature Review.

机构信息

School of Nursing, Wichita State University College of Health Professions, 1845 Fairmount Street, Ahlberg Hall Rm 500, Wichita, KS 67260, USA. Tel 316-978-5719.

出版信息

J Allied Health. 2021 Spring;50(1):73-83.

PMID:33646253

Abstract

BACKGROUND

Dental caries (cavities) and anemia are among the most common chronic diseases seen by health professionals and experienced globally. However, the quality, and current evidence linking pediatric dental caries to anemia, is not well established. Moreover, it is not well known whether anemia seen with dental caries is due to iron deficiency or other causes.

OBJECTIVE

This systematic literature review was designed to analyze the relationship between anemia and pediatric dental caries and examine the strength of evidence in current research.

METHODS

Articles were sourced from PubMed, the American Dental Association database, American Dental Hygienist's Association database, Science Direct, Cochrane Library, CINAHL, Google Scholar, and Medline ProQuest. Outcomes were pooled for statistical effect size.

RESULTS

Nineteen articles were selected from 351 identified. There was a 4.5-fold incidence in anemia diagnosis among children with, compared to without, dental caries. While ferritin and mean corpuscular volume were not significantly different among children with and without dental caries, the average serum iron was nearly 30 ug/dL greater in caries-free children, suggesting that iron deficiency may be more common among children with caries. Studies in the future may benefit from methodological improvements and more specific study questions to further investigate this question.

摘要

背景

龋齿（蛀牙）和贫血是全球范围内医疗保健专业人员常见的最常见的慢性疾病之一。然而，将儿科龋齿与贫血联系起来的研究质量和现有证据并不完善。此外，尚不清楚与龋齿相关的贫血是由缺铁还是其他原因引起的。

目的

本系统文献回顾旨在分析贫血与儿科龋齿之间的关系，并检查当前研究中的证据强度。

方法

文章来源包括 PubMed、美国牙医协会数据库、美国牙卫生师协会数据库、Science Direct、Cochrane 图书馆、CINAHL、Google Scholar 和 Medline ProQuest。对结果进行汇总以进行统计效应大小分析。

结果

从 351 篇已识别文献中选择了 19 篇文章。与无龋齿的儿童相比，患有龋齿的儿童贫血诊断的发生率高 4.5 倍。虽然铁蛋白和平均红细胞体积在有龋齿和无龋齿的儿童之间没有显著差异，但无龋齿儿童的平均血清铁含量高出近 30ug/dL，这表明缺铁在龋齿儿童中可能更为常见。未来的研究可能受益于方法学的改进和更具体的研究问题，以进一步调查这个问题。