Department of Pediatrics, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey.
Departments of Pediatrics and Neonatal Intensive Care Unit, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey.
Int Arch Occup Environ Health. 2021 Oct;94(7):1627-1636. doi: 10.1007/s00420-021-01665-3. Epub 2021 Mar 1.
During the COVID-19 pandemic, healthcare professionals are recommended to use PPE to prevent the transmission of disease. Healthcare workers who use N95 FFR, which has an important place, experience complaints such as headache and dizziness. In this study, we plan to find the cause of these complaints and aim to clarify whether they are associated with the use of N95 mask.
Healthcare workers first put on a surgical mask for at least 1 h and a maximum of 4 h, this process was then repeated on another day with the same workers wearing N95 masks. After removing the mask, capillary blood gases were taken and a questionnaire was given.
Thirty-four participants over the age of 18 were included in the study; 19 participants were female (56%) and 15 male (44%). The results of the capillary blood gas analysis after the use of surgical mask and N95 mask, respectively: pH: 7.43 ± 0.03; 7.48 ± 0.04 (p < 0.001); pCO: 37.33 ± 8.81; 28.46 ± 7.77 mmHg (p < 0.001); HCO: 24.92 ± 2.86; 23.73 ± 3.29 mmol/L (p = 0.131); Base excess (BE): 1.40 (- 3.90-3.10); - 2.68 (- 4.50-1.20) [median (Q1-Q3)] (p = 0.039); lactate: 1.74 ± 0.68; 1.91 ± 0.61 (p = 0314). Headache, attention deficit and difficulty in concentrating were significantly higher after using N95 mask.
Respiratory alkalosis and hypocarbia were detected after the use of N95. Acute respiratory alkalosis can cause headache, anxiety, tremor, muscle cramps. In this study, it was quantitatively shown that the participants' symptoms were due to respiratory alkalosis and hypocarbia.
在 COVID-19 大流行期间，建议医护人员使用个人防护设备（PPE）来预防疾病传播。使用 N95 FFR（具有重要地位）的医护人员会出现头痛和头晕等不适。在这项研究中，我们计划找到这些不适的原因，并旨在阐明它们是否与 N95 口罩的使用有关。
医护人员首先佩戴外科口罩至少 1 小时，最长 4 小时，然后在另一天让同一批人员重复佩戴 N95 口罩。摘下口罩后，采集毛细血管血气并发放问卷。
研究纳入了 34 名年龄在 18 岁以上的参与者；19 名参与者为女性（56%），15 名男性（44%）。分别使用外科口罩和 N95 口罩后的毛细血管血气分析结果：pH 值：7.43±0.03；7.48±0.04（p<0.001）；pCO2：37.33±8.81；28.46±7.77mmHg（p<0.001）；HCO3-：24.92±2.86；23.73±3.29mmol/L（p=0.131）；碱剩余（BE）：1.40（-3.90-3.10）；-2.68（-4.50-1.20）[中位数（Q1-Q3）]（p=0.039）；乳酸：1.74±0.68；1.91±0.61（p=0.314）。使用 N95 口罩后，头痛、注意力不集中和注意力集中困难的发生率明显更高。
使用 N95 口罩后检测到呼吸性碱中毒和低碳酸血症。急性呼吸性碱中毒可引起头痛、焦虑、震颤、肌肉痉挛。在这项研究中，定量显示参与者的症状是由呼吸性碱中毒和低碳酸血症引起的。
