回顾性研究 182 例犬剖宫产手术中使用腰荐硬膜外腔镇痛的效果：对血压、镇痛药物使用和手术时间的影响。

Retrospective study on the use of lumbosacral epidural analgesia during caesarean section surgery in 182 dogs: Impact on blood pressure, analgesic use and delays.

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

出版信息

Vet Rec. 2021 Apr;188(8):e134. doi: 10.1002/vetr.134. Epub 2021 Mar 1.

DOI:10.1002/vetr.134

PMID:33646571

Abstract

BACKGROUND

We evaluated the use of lumbosacral epidural anaesthesia (LEA) in dogs undergoing caesarean section over 10 years.

METHODS

Anaesthetic records were reviewed and divided into two treatment groups: LEA and control. Outcome variables identified a priori as potentially affected by LEA were compared between groups. Results are frequency or median (minimum-maximum).

RESULTS

Ninety-five dogs received LEA and 87 did not. LEA consisted of 0.2 (0.1-0.3) ml/kg containing bupivacaine (n = 63), ropivacaine (n = 15), or lidocaine (n = 12) at concentrations ranging between 0.06% and 2%. Morphine, fentanyl, or buprenorphine were used as part of LEA. Groups were similar for demographic variables (all p > 0.06). Intravenous opioids were used more often in control than in LEA (p < 0.0005). Incidence of hypotension (MAP < 60 mm Hg) was LEA 68% and control 56% (p = 0.12). Duration of hypotension was longer in LEA (p = 0.03). Use of crystalloids and vasoactive drugs did not differ (all p > 0.1). Time from induction to operating room was 30 (8-75) min for control and 35 (18-65) min for LEA (p = 0.003).

DISCUSSION

LEA during caesarean section in dogs was associated with lower rates of opioid administration and did not exacerbate the incidence of hypotension.

摘要

背景

我们评估了在 10 多年间对行剖宫产术的犬使用腰荐硬膜外麻醉（LEA）的效果。

方法

回顾麻醉记录并分为两组治疗：LEA 组和对照组。预先确定的可能受 LEA 影响的结局变量在组间进行比较。结果以频率或中位数（最小值-最大值）表示。

结果

95 只犬接受了 LEA，87 只犬未接受。LEA 包括 0.2（0.1-0.3）ml/kg 的布比卡因（n=63）、罗哌卡因（n=15）或利多卡因（n=12），浓度在 0.06%至 2%之间。吗啡、芬太尼或丁丙诺啡被用作 LEA 的一部分。两组在人口统计学变量方面相似（均 p>0.06）。在对照组中，静脉内使用阿片类药物的频率高于 LEA 组（p<0.0005）。LEA 组的低血压（MAP<60mmHg）发生率为 68%，对照组为 56%（p=0.12）。LEA 组低血压持续时间更长（p=0.03）。晶体和血管活性药物的使用无差异（均 p>0.1）。从诱导到手术室的时间对照组为 30（8-75）min，LEA 组为 35（18-65）min（p=0.003）。